1
Archana Gangakhedkar, Xuedong Dai, Noa Zerangue, Peter A Virsik: Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use. XenoPort, Polsinelli PC, July 15, 2014: US08778991 (43 worldwide citation)

Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions comprising prodrugs of methyl hydrogen fumarate, and methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel ...


2
Mark A Gallop, Xuedong Dai, Randall A Scheuerman, Stephen P Raillard, Suresh K Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat: Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof. XenoPort, Dorsey & Whitney, June 5, 2007: US07227028 (34 worldwide citation)

Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful int ...


3
Archana Gangakhedkar, Xuedong Dai, Noa Zerangue, Peter A Virsik: Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use. XenoPort, Dorsey & Whitney, April 3, 2012: US08148414 (17 worldwide citation)

Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions comprising prodrugs of methyl hydrogen fumarate, and methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel ...


4
Jia Ning Xiang, Mark A Gallop, Cindy X Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C Cundy, Nelson L Jumbe: Levodopa prodrugs, and compositions and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner L, March 11, 2008: US07342131 (16 worldwide citation)

Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.


5
Jia Ning Xiang, Xuedong Dai, Cindy X Zhou, Jianhua Li, Mark Q Nguyen: Levodopa prodrug mesylate, compositions thereof, and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner, February 22, 2011: US07893105 (15 worldwide citation)

(2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided.


6
Jia Ning Xiang, Xuedong Dai, Cindy X Zhou, Jianhua Li, Mark Q Nguyen: Levodopa prodrug mesylate, compositions thereof, and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner, July 21, 2009: US07563821 (14 worldwide citation)

(2R)-2-Phenylcarbonyloxypropyl(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided.


7
Jia Ning Xiang, Mark A Gallop, Cindy X Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C Cundy, Nelson L Jumbe: Levodopa prodrugs, and compositions and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner, May 19, 2009: US07534813 (14 worldwide citation)

Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.


8
Jia Ning Xiang, Mark A Gallop, Cindy X Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C Cundy: Levodopa prodrugs, and compositions and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner L, January 29, 2008: US07323585 (13 worldwide citation)

Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.


9
Mark A Gallop, Xuedong Dai, Randall A Scheuerman, Stephen P Raillard, Suresh K Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat: Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof. XenoPort, Dorsey & Whitney, March 31, 2009: US07511158 (12 worldwide citation)

Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful int ...


10
Jia Ning Xiang, Mark A Gallop, Cindy X Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C Cundy, Nelson L Jumbe: Levodopa prodrugs, and compositions and uses thereof. XenoPort, Finnegan Henderson Farabow Garrett & Dunner, March 2, 2010: US07671089 (8 worldwide citation)

Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.