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Walker George, Xu Junquan, Yamanishi Douglas, Hujsak Paul, Wu Lei, Huang Mingxian, Tao Guoliang, Snyder Sara, Yap Charina: Methods, compositions, and automated systems for separating rare cells from fluid samples. Aviva Biosciences Corporation, Walker George, Xu Junquan, Yamanishi Douglas, Hujsak Paul, Wu Lei, Huang Mingxian, Tao Guoliang, Snyder Sara, Yap Charina, PRESTON David, May 26, 2005: WO/2005/047529 (28 worldwide citation)

The invention includes microfabricated filters for filtering fluid samples and methods of enriching rare cells of fluid samples using microfabricated filters of the present invention. The invention also includes solutions for the selective sedimentation of red blood cells (RBCs) from a blood sample ...


2
Yamanishi Douglas, Hujsak Paul, Yang Zhaohuai, Xu Junquan, Wang Xiaobo, Wu Lei, Huang Mingxian, Tao Guoliang, Cheng Jing: Methods for separating rare cells from fluid samples. Aviva Biosciences, July 28, 2004: EP1439897-A2 (3 worldwide citation)

The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnor ...


3
Yamanishi Douglas, Hujsak Paul, Yang Zhaohuai, Xu Junquan, Wang Xiaobo, Wu Lei, Huang Mingxian, Tao Guoliang, Cheng Jing: Methods, compositions, and automated systems for separating rare cells from fluid samples. Aviva Biosciences Corporation, PRESTON David, April 17, 2003: WO/2003/031938 (3 worldwide citation)

The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnor ...


4
Xu Junquan, Wang Xiaobo, Cheng Jing, Yang Weiping, Wu Lei: Compositions and methods for separation of moieties on chips. Aviva Biosciences, July 9, 2003: EP1325331-A1 (2 worldwide citation)

The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for the separation of moieties in a sample based on their dielectri ...


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Walker George, Xu Junquan, Yamanishi Douglas, Hujsak Paul, Wu Lei, Huang Mingxian, Tao Guoliang, Snyder Sara, Yap Charina: Methods, compositions, and automated systems for separating rare cells from fluid samples. Aviva Biosciences, August 30, 2006: EP1694856-A1 (2 worldwide citation)

The invention includes microfabricated filters for filtering fluid samples and methods of enriching rare cells of fluid samples using microfabricated filters of the present invention. The invention also includes solutions for the selective sedimentation of red blood cells (RBCs) from a blood sample ...


6
Wang Xiaobo, Wu Lei, Cheng Jin, Yang Weiping, Xu Junquan: Methods for manipulating moieties in microfluidic systems. Aviva Biosciences Corporation, CHEN Peng, February 14, 2002: WO/2002/012896 (2 worldwide citation)

This invention relates generally to the field of moiety or molecule manipulation in a chip format. In particular, the invention provides a method for manipulating a moiety in a microfluidic application, which method comprises: a) coupling a moiety to be manipulated onto surface of a binding partner ...


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Cheng Jing, Wang Xiaobo, Wu Lei, Yang Weiping, Xu Junquan: An integrated biochip system for sample preparation and analysis. Aviva Biosciences Corporation, sPRESTON David, April 18, 2002: WO/2002/030562 (2 worldwide citation)

The invention includes a composition that is an integrated biochip system for processing and analyzing samples using sequential tasks that take place on one or more chips. The system preferably comprises one or more active chips, and can be automated. The invention also includes methods of using an ...


9
Xu Junquan, Wang Xiaobo, Cheng Jing, Yang Weiping, Wu Lei: Compositions and methods for separation of moieties on chips. Aviva Biosciences Coropration, PRESTON David, April 18, 2002: WO/2002/031506 (2 worldwide citation)

The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for the separation of moieties in a sample based on their dielectri ...


10
Shao Wei, Xu Junquan, Xing Wan Li, Cheng Jing: Integrated microarray devices. Capital Biochip Company, Univ Tsinghua, April 9, 2003: EP1299564-A2 (1 worldwide citation)

This invention relates generally to the field of microarray technology. In particular, the invention provides an integrated macroarray device, which device comprises a substrate comprising a plurality of distinct microlocations and a plurality of microarray chips, wherein the number of said microloc ...