1
Michael P Nova, Hanan Potash, Xiao Yi Xiao, Zahra Parandoosh, Gary S David: Method for tagging and screening molecules. Discovery Partners International, Kilpatrick Stockton, November 20, 2001: US06319668 (218 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


2
Michael P Nova, Zahra Parandoosh, Andrew E Senyei, Xiao Yi Xiao, Gary S David, Yozo Satoda, Chanfeng Zhao, Hanan Potash: Matrices with memories and uses thereof. Irori, Brown Martin Haller & McClain, October 5, 1999: US05961923 (214 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


3
Michael P Nova, Zahra Parandoosh, Andrew E Senyei, Xiao Yi Xiao, Gary S David, Yozo Satoda, Chanfeng Zhao, Hanan Potash: Matrices with memories and uses thereof. Irori, Brown Martin Haller & McClain, January 25, 2000: US06017496 (154 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


4
Michael P Nova, Andrew E Senyei, Xiao Yi Xiao, Chanfeng Zhao, Hanan Potash: Solid support matrices with memories and combinatorial libraries therefrom. Discovery Partners International, Brown Martin Haller & McClain, September 4, 2001: US06284459 (91 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


5
Xiao Yi Xiao: Histone deacetylase inhibitors. Takeda San Diego, David J Weitz, July 31, 2007: US07250514 (23 worldwide citation)

Histone deacetylase inhibitors and uses thereof are provided that have the general formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, M and L have the definitions as described herein.


6
Chanfeng Zhao, John E Lillig, Robert Neeper, Gordon W Hudson, Anthony W Czarnik, Zahra Parandoosh, Gary S David, Xiao Yi Xiao: Radiation-grafted solid supports for chemical synthesis. Irori, Kilpatrick Stockton, October 23, 2001: US06306975 (19 worldwide citation)

Methods for irradiation induced graft polymerization of a monomers, such as styrenes, onto fluoropolymers are provided. The methods, which involve either the use of acids, preferably mineral acids, or creating a rough surface on the fluoropolymer, provide higher levels of grafting of the copolymer t ...


7
David A Campbell, Dinesh V Patel, Xiao Yi Xiao: Inhibitors of collagenase-1 and stormelysin-I metalloproteases, pharmaceutical compositions comprising same and methods of their use. Affymax Technologies, Gerald F Swiss, Lauren L Stevens, November 24, 1998: US05840698 (16 worldwide citation)

Disclosed are novel inhibitors of collagenase-1 and stromelysin-I metalloproteases. The disclosed inhibitors are mercaptoketone and mercaptoalcohol compounds which are useful in pharmaceutical compositions and methods for treating or controlling disease states or conditions which involve tissue brea ...


8
Xiao Yi Xiao, Dinesh V Patel: Cytotoxic agents and methods of use. Miikana Therapeutics, King & Spalding, May 13, 2008: US07371875 (15 worldwide citation)

Disclosed are compounds that inhibit proteasomic activity in cells. Also disclosed are pharmaceutical compositions comprising such compounds as well as methods to treat conditions, particularly cell proliferative conditions, such as cancer and inflammatory conditions.


9
Jerome C Bressi, Jason W Brown, Sheldon X Cao, Anthony R Gangloff, Andrew J Jennings, Jeffrey A Stafford, Phong H Vu, Xiao Yi Xiao: Histone deacetylase inhibitors. Takeda San Diego, David J Weitz, January 30, 2007: US07169801 (14 worldwide citation)

Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0–10 atoms separation between the M substituent and the remainder ...


10
Sampath K Anandan, Xiao Yi Xiao, Dinesh V Patel, John Ward: Inhibitors of histone deacetylase. Miikana Therapeutics, King & Spalding, March 18, 2008: US07345043 (14 worldwide citation)

Disclosed are compounds which inhibit histone deacetylase (HDAC) enzymatic activity. Also disclosed are pharmaceutical compositions comprising such compounds as well as methods to treat conditions, particularly proliferative conditions, mediated at least in part by HDAC.