1
Wu Bo Li, Christian E Gruber, Joel A Jessee, Jhy Jhu Lin: Method of nucleic acid sequence selection. Life Technologies, Jeffrey I Auerbach Esq, Kevin W McCabe, Howrey & Simon, June 2, 1998: US05759778 (63 worldwide citation)

The present invention provides a method for the rapid isolation and recovery of a desired target DNA or RNA molecules from a mixture or library containing such molecules. The method involves the use of biotinylated probes and enzymatic repair-cleavage to eliminate undesired library members from a sa ...


2
Wu Bo Li, Joel A Jessee, David Schuster, Jiulin Xia, Gulilat Gebeyehu: Compositions and methods for enhanced synthesis of nucleic acid molecules. Invitrogen Corporation, Sterne Kessler Goldstein & Fox P L L C, September 7, 2004: US06787305 (42 worldwide citation)

The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from ...


3
Wu Bo Li, Christian E Gruber, Joel A Jessee, Jhy Jhu Lin: Method of nucleic acid sequence selection. Life Technologies, Howrey & Simon, March 19, 1996: US05500356 (21 worldwide citation)

The present invention provides a method for the rapid isolation and recovery of a desired target DNA or RNA molecules from a mixture or library containing such molecules. The method involves the use of biotinylated probes and enzymatic repair-cleavage to eliminate undesired library members from a sa ...


4
Wu Bo Li, Paul E Nisson, Joel Jessee: Normalized nucleic acid libraries and methods of production thereof. Invitrogen Corporation, Sterne Kessler Goldstein & Fox P L L C, June 4, 2002: US06399334 (18 worldwide citation)

The present invention relates generally to methods for producing normalized nucleic acid libraries in which each member of the library can be isolated with approximately equivalent probability. In particular, the present methods comprise subtractive hybridization of a nucleic acid library with hapte ...


5
LU Qi Long, WU Bo: Compositions pharmaceutiques comprenant des oligonucleotides antisens et procedes dutilisation de ceux-ci, Pharmaceutical compositions comprising antisense oligonucleotides and methods of using same. The Charlotte Mecklenburg Hospital Authority D B A Carolinas Medical Center, LU Qi Long, WU Bo, BALTS Timothy J, November 17, 2011: WO/2011/143008 (17 worldwide citation)

The invention provides compositions and associated methods for the antisense treatment of genetic disorders, infections and various other medical conditions. In particular, embodiments of the present invention are directed to pharmaceutical compositions comprising a combination of an antisense oligo ...


6
Paul E Nisson, Joel Jesse, Wu bo Li: Method for isolating and recovering target DNA or RNA molecules having a desired nucleotide sequence. Invitrogen Corporation, Sterne Kessler Goldstein & Fox P L L C, July 31, 2001: US06268133 (14 worldwide citation)

The invention generally concerns the use of amino acid denaturants for denaturing or separating double stranded nucleic acid molecules. More specifically, the present invention provides a method for the rapid isolation and recovery of a desired target DNA or RNA molecules from a mixture or library c ...


7

8
Hu Fang, Wu Bo: Hyperthermia oncolysis co-therapy. Shanghai Sunway Biotech, Hu Fang, Wu Bo, CHWANG T Ling, August 12, 2004: WO/2004/066947 (6 worldwide citation)

The present invention relates to compositions and methods for ablating tumor cells in a subject having at least one tumor site. More specifically, the method comprises contacting the tumor cells in at least one tumor with a lytic agent in vivo, under lytic conditions, forming a treated tumor; and ap ...


9
Wu Bo Li, Joel A Jessee, Christian E Gruber: cDNA synthesis improvements. Invitrogen Corporation, Sterne Kessler Goldstein & Fox PLLC, July 11, 2006: US07074556 (5 worldwide citation)

The present invention generally relates to methods of making cDNA molecules and cDNA libraries. The invention also relates to cDNA molecules and cDNA libraries produced according to these methods, as well as to vectors and host cells containing such cDNA molecules and libraries. The invention also r ...


10
Paul E Nisson, Joel Jesse, Wu bo Li: Method for isolating and recovering target DNA or RNA molecules having a desired nucleotide sequence. Invitrogen Corporation, Sterne Kessler Goldstein & Fox P L L C, April 5, 2005: US06875568 (5 worldwide citation)

The invention generally concerns the use of amino acid denaturants for denaturing or separating double stranded nucleic acid molecules. More specifically, the present invention provides a method for the rapid isolation and recovery of a desired target DNA or RNA molecules from a mixture or library c ...



Click the thumbnails below to visualize the patent trend.