1
Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc, REID Scott W, May 4, 2006: WO/2006/047516 (17 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


2
Liu Hong, Alper Phil, Chatterjee Arnab, Tully David, Bursulaya Badry, Woodmansee David, Epple Robert, Harris Jennifer Leslie, Li Jun: Inhibitors of cathepsin s. Irm, Liu Hong, Alper Phil, Chatterjee Arnab, Tully David, Bursulaya Badry, Woodmansee David, Epple Robert, Harris Jennifer Leslie, Li Jun, SNYDER Joseph R, October 7, 2004: WO/2004/084843 (1 worldwide citation)

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease stat ...


3
Liu Hong, Tully David C, Chatterjee Arnab, Alper Phillip B, Woodmansee David H, Mutnick Daniel: Compounds and compositions as cathepsin s inhibitors. Irm, Liu Hong, Tully David C, Chatterjee Arnab, Alper Phillip B, Woodmansee David H, Mutnick Daniel, REID Scott W, November 17, 2005: WO/2005/107464 (1 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cathepsin S.


4
Liu Hong, Chatterjee Arnab, Tully David C, Alper Phillip B, Bursulaya Badry, Guo Jianhua, Woodmansee David, Mutnick Daniel, Karanewsky Donald S, He Yun: Inhibitors of cathepsin s. Irm, May 24, 2006: EP1658267-A2

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease stat ...


5
He Yun, Woodmansee David, Choi Ha Soon, Wang Zhicheng, Wu Baogen, Nguyen Truc: Synthesis of aryl pyrrolidones. Irm, linbai nan liujin hui, January 23, 2008: CN200680003553

The invention provides methods of asymmetrically synthesizing aryl pyrrolidones with high yield and high enantionmeric excess.


6
Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc: Composes et compositions servant dinhibiteurs dactivite de recepteur cannabinoide de type 1, Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Irm, Fetherstonhaugh & Co, October 25, 2011: CA2581225

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


7

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Liu Hong, Tully David C, Chatterjee Arnab, Alper Phillip B, Woodmansee David H, Mutnick Daniel: Compounds and compositions as cathepsin s inhibitors. Irm, January 24, 2007: EP1744755-A2

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cathepsin S.


9
Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, July 18, 2007: EP1807429-A2

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


10
Liu Hong, Chatterjee Arnab, Tully David C, Alper Phillip B, Bursulaya Badry, Guo Jianhua, Woodmansee David, Mutnick Daniel, Karanewsky Donald S, He Yun: Inhibitors of cathepsin s. Irm, Liu Hong, Chatterjee Arnab, Tully David C, Alper Phillip B, Bursulaya Badry, Guo Jianhua, Woodmansee David, Mutnick Daniel, Karanewsky Donald S, He Yun, SNYDER Joseph R, April 21, 2005: WO/2005/034848

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease stat ...