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Martin Bechem, Wolfgang Paffhausen: Fluorescence-measuring system. Bayer HealthCare Aktiengesellschaft, January 10, 2006: US06985225 (6 worldwide citation)

The invention relates to a fluorescence-measuring system as can be employed for high-throughput screening in drug development. The arrangement for fluorescence excitation contains a two-dimensionally extended sample-receiving device and at least two illumination sources for exciting the fluorescence ...


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Thoams Krahn, Wolfgang Paffhausen, Andreas Schade, Martin Bechem, Delf Schmidt: Masking background flourescence and luminescence in optical analysis of biomedical assays. Bayer Healthcare, Norris McLaughlin & Marcu P A, June 20, 2006: US07063952 (5 worldwide citation)

In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact with a solution 3 containing the fluorescent dye 4. The sensitivity of analytical detection can be considerably ...


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Thomas Krahn, Wolfgang Paffhausen, Andreas Schade, Martin Bechem, Delf Schmidt: Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays. Bayer Healthcare, Norris McLaughlin & Marcus PA, November 21, 2006: US07138280 (4 worldwide citation)

In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which absorbs the excitation light for the fluorescent dye and/or its emission light is added to the solution ...


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Thoams Krahn, Wolfgang Paffhausen, Andreas Schade, Martin Bechem, Delf Schmidt: Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays. Bayer Healthcare, Norris McLaughlin & Marcus P A, May 15, 2012: US08178359 (3 worldwide citation)

A process for the quantitative optical analysis of fluorescently labeled biological cells involves contacting a cell layer on a transparent support at the bottom of a reaction vessel with a solution containing the fluorescent dye. This process can also be used for improving the sensitivity in the qu ...


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Thomas Krahn, Wolfgang Paffhausen, Andreas Schade, Martin Bechem, Delf Schmidt: Masking background fluorescence and luminescence in the optical analysis of biomedical assays. Bayer Schering Pharma Aktiengesellschaft, Norris McLaughlin & Marcus PA, November 10, 2009: US07615376 (3 worldwide citation)

In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact with a solution 3 containing the fluorescent dye 4. The sensitivity of analytical detection can be considerably ...


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Rainer Gross, Wolfgang Paffhausen, Andreas Schade, Gerd Heusch: Process for the measurement of blood circulation by means of non-radioactive microspheres. Triton Technology, William C Fuess, October 19, 1993: US05253649 (1 worldwide citation)

An improved process for the measurement of blood circulation by means of colored microspheres is presented, which process replaces the previous counting procedure when using colored microspheres by a rapidly reproducible measurement method. This avoids the complicated and expensive use of radioactiv ...


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Karsten Reihs, Wolfgang Paffhausen: Ultraphobic surface structure having a plurality of hydrophilic areas. Qiagen, Oblon Spivak McClelland Maier & Neustadt L, December 15, 2009: US07632466

Disclosed is an ultraphobic surface structure, especially a microtitre plate and a method for the production thereof which is provided with a plurality of hydrophilic areas which are preferably distributed on the surface in a periodic manner.


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Martin Bechem, Wolfgang Paffhausen: Fluorescence-measuring system. Jeffrey M Greenman, Vice President Patents and Licensing, February 19, 2004: US20040032589-A1

The invention relates to a fluorescence-measuring system as can be employed for high-throughput screening in drug development. The arrangement for fluorescence excitation contains a two-dimensionally extended sample-receiving device and at least two illumination sources for exciting the fluorescence ...