1
Peter C Lord, William P Van Antwerp, John J Mastrototaro, Paul S Cheney II, Nannette M Schnabel: Transcutaneous sensor insertion set. MiniMed, Kelly Bauersfeld & Lowry, February 21, 1995: US05390671 (1100 worldwide citation)

An insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a slotted insertion needle extending through a mounting base adapted for mounting onto the patient's skin. A flexible thin film ...


2
Paul S Cheney II, William P Van Antwerp: Method of fabricating thin film sensors. MiniMed, Kelly Bauersfeld & Lowry, February 21, 1995: US05391250 (1086 worldwide citation)

An improved method is provided for making thin film electrochemical sensors, such as subcutaneous glucose sensors used to monitor blood glucose levels in a diabetic patient. The fabrication method comprises placing a thin film base layer of insulative material onto a rigid flat substrate, with a cur ...


3
Garry M Steil, Kerstin Rebrin, Paul V Goode Jr, John J Mastrototaro, Richard E Purvis, William P Van Antwerp, John J Shin, Cary D Talbot: Closed loop system for controlling insulin infusion. Medtronic MiniMed, Medtronic MiniMed, May 6, 2003: US06558351 (1083 worldwide citation)

A closed loop infusion system controls the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signa ...


4
Paul S Cheney II, John J Mastrototaro, Nannette M Schnabel, Peter C Lord, William P Van Antwerp, Raymond D Clark: Transcutaneous sensor insertion set. MiniMed, Kelly Bauersfeld & Lowry, October 29, 1996: US05568806 (808 worldwide citation)

An improved insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises an insertion needle extending through a mounting base adapted for mounting onto the patient's skin. A flexible thin fil ...


5
Peter C Lord, William P Van Antwerp, John J Mastrototaro, Paul S Cheney II, Nannette M Schnabel: Flex circuit connector. Minimed, Kelly Bauersfeld & Lowry, January 9, 1996: US05482473 (568 worldwide citation)

A connector is provided for electrical connection to a flex circuit in a hermetically sealed manner. The flex circuit comprises thin film conductors encased between layers of insulative material, and including a proximal end with conductive contact pads exposed through one of the insulative layers. ...


6
William P Van Antwerp: Polyurethane/polyurea compositions containing silicone for biosensor membranes. MiniMed, Townsend and Townsend and Crew, March 16, 1999: US05882494 (563 worldwide citation)

A homogenous polymer composition useful as a membrane for biosensors is disclosed. The polymer composition comprises the reaction products of a diisocyanate, a hydrophilic diol or diamine, and a silicone material. An aliphatic diol or diamine may also be included. Membranes prepared from the composi ...


7
James D Holker, Guillermo A Calle, Kevin D Branch, John J Mastrototaro, William P Van Antwerp, Nannette Van Antwerp: Analyte sensor method of making the same. Medtronic MiniMed, Medtronic MiniMed, February 21, 2006: US07003336 (525 worldwide citation)

A sensor and method of making the same for implantation in a body that includes a substrate with notches cut in the substrate to form a necked down region in the substrate; and at least one sensor electrode formed from one or more conductive layers. Preferably, the thickness of the substrate ranges ...


8
William P Van Antwerp, John J Mastrototaro: Sensor including UV-absorbing polymer and method of manufacture. MiniMed, Gates & Cooper, July 2, 2002: US06413393 (445 worldwide citation)

A sensor is provided that includes at least one functional coating layer that includes a UV-absorbing polymer. Methods for making the inventive sensors are also provided.


9
James D Holker, Guillermo A Calle, Kevin D Branch, John J Mastrototaro, William P Van Antwerp: Analyte sensor and method of making the same. Medtronic MiniMed, Medtronic MiniMed, November 19, 2002: US06484045 (440 worldwide citation)

A method of making a sensor includes the steps of providing a preformed self-supporting flexible substrate; sputter-depositing a metal layer on the substrate; etching the sputter-deposited metal layers to form a sensor electrode having a proximal segment and a distal segment; plating a metal layer o ...


10
William P Van Antwerp, John J Mastrototaro: Reusable analyte sensor site and method of using the same. Medtronic Minimed, Medtronic Minimed, April 9, 2002: US06368274 (431 worldwide citation)

A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing. Preferably, the site housing material is formed to have an interior cavity with an opening and a conduit that is connected to the opening of the interior tissue ing ...