1
Daniel J Capon, Richard M Lawn, Arthur D Levinson, Gordon A Vehar, William I Wood: Preparation of functional human factor VIII in mammalian cells using methotrexate based selection. Genentech, Janet E Hasak, October 23, 1990: US04965199 (114 worldwide citation)

A method for producing factor VIII in recombinant mammalian host cells utilizing an expression vector containing a selectable marker DNA and an amplifiable marker DNA. The initial selection is based upon the selectable marker and subsequent amplification of factor VIII DNA and amplifiable marker DNA ...


2
Audrey Goddard, Paul J Godowski, Austin L Gurney, Margaret Ann Roy, William I Wood: Secreted and transmembrane polypeptides and nucleic acids encoding the same. Genentech, Elizabeth M Barnes, Mark T Kresnak, Heller Ehrman White & McAuliffe, July 12, 2005: US06916648 (46 worldwide citation)

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to het ...


3
R Glenn Hammonds, David W Leung, Steven A Spencer, William I Wood: Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein. Genentech, Robert H Benson, Max D Hensley, October 15, 1991: US05057417 (43 worldwide citation)

Growth hormone receptor and growth hormone binding protein are purified enabling amino acid sequence and DNA isolates coding for growth hormone receptor and growth hormone binding protein and methods of obtaining such DNA are provided, together with expression systems for recombinant production of g ...


4
Austin L Gurney, Sudeepta Aggarwal, Ming Hong Xie, Ellen M Maruoka, Jessica S Foster, Audrey Goddard, William I Wood: Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders. Genentech, David A Carpenter, April 22, 2003: US06551799 (32 worldwide citation)

The present invention is directed to interleukin-22 polypeptides and nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused ...


5
Avi Ashkenazi, Sherman Fong, Audrey Goddard, Austin L Gurney, Mary A Napier, Daniel Tumas, William I Wood: Nucleic acids encoding A-33 related antigen polypeptides. Genentech, Elizabeth M Barnes, June 25, 2002: US06410708 (30 worldwide citation)

The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer, and nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, ...


6
Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P Mickey Williams, William I Wood, Daniel Yansura: IL-17 homologous polypeptides and therapeutic uses thereof. Genentech, Elizabeth M Barnes, May 27, 2003: US06569645 (27 worldwide citation)

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to het ...


7
Avi Ashkenazi, David Botstein, Luc Desnoyers, Dan L Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei Qiang Gao, Hanspeter Gerber, Mary E Gerritsen, Audrey Goddard, Paul J Godowski, J Christopher Grimaldi, Austin L Gurney, Kenneth J Hillan, Ivar J Kljavin, Jennie P Mather, James Pan, Nicholas F Paoni, Margaret Ann Roy, Timothy A Stewart, Daniel Tumas, P Mickey Williams, William I Wood: Secreted and transmembrane polypeptides and nucleic acids encoding the same. Genentech, Elizabeth M Barnes, Mark T Kresnak, Ginger R Greger Esq, October 21, 2003: US06635468 (27 worldwide citation)

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to het ...


8
Robert C Baxter, William I Wood: DNA encoding and methods of production of insulin-like growth factor binding protein BP53. Genentech, Central Sydney Area Health Service, Janet E Hasak, November 2, 1993: US05258287 (25 worldwide citation)

DNA isolates coding for insulin-like growth factor binding protein may be used to produce the protein via recombinant expression systems. Insulin-like growth factor binding protein, which generally has a molecular weight of about 53 kD on non-reducing SDS-PAGE, is useful as a binder to insulin-like ...


9
Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P Mickey Williams, William I Wood, Daniel Yansura: IL-17 related mammalian cytokine polypeptides (IL-17E). Genentech, Elizabeth M Barnes, June 17, 2003: US06579520 (24 worldwide citation)

The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising t ...


10
R Glenn Hammonds, David W Leung, David W Martin Jr, Steven A Spencer, William I Wood: Methods and compositions for immunologically modulating growth hormone receptor activity. Genentech, Max D Hensley, August 15, 1989: US04857637 (24 worldwide citation)

The activity of growth-associated receptors is modulated in vivo in a controlled and reproducible fashion by immunizing animals against target growth-associated receptors. This is accomplished by the use of immunogens predetermined to induce primarily agonist or antagonist responses. The immunogens ...



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