1
Amarpreet S Sawhney, David J Enscore, Stephen D Goodrich, William C Nason, Fei Yao, Douglas Weaver, Peter K Jarrett, Arthur J Coury, Ronald S Rudowsky, Michelle D Powell, Luis Z Avila, Shikha P Barman: Polymerizable biodegradable polymers including carbonate or dioxanone linkages. Focal, Arnall Golden & Gregory, July 4, 2000: US06083524 (78 worldwide citation)

Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers are preferably polymerized using fr ...


2
Amarpreet S Sawhney, Peter K Jarrett, Arthur J Coury, Ronald S Rudowsky, Michelle D Powell, Luis Z Avila, David J Enscore, Stephen D Goodrich, William C Nason, Fei Yao, Douglas Weaver, Shikha P Barman: Polymerizable biodegradable polymers including carbonate or dioxanone linkages. Focal, Arnall Golden & Gregory, January 23, 2001: US06177095 (63 worldwide citation)

Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers are preferably polymerized using fr ...


3
Ronald A LeMahieu, William C Nason: Trans-3-(4-oxo-4H-quinazolin-3-yl)-2-propenoic acid derivatives. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, William G Isgro, July 28, 1981: US04281127 (22 worldwide citation)

Trans-3-(4-oxo-4H-quinazolin-3-yl)-2-propenoic acid derivatives of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, lower cycloalkyl, lower alkoxy, hydroxy, halo, lower alkykthio, lower alkylsulfinyl, lower alkylsulfonyl, di-(C.sub.1 -C.sub.7)alkyl-N(CH.sub.2).sub.n O-- or 2-hydroxyeth ...


4
Matthew Carson, Ronald A LeMahieu, William C Nason: Phenoxycarboxylic acids. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, Matthew Boxer, March 26, 1985: US04507498 (12 worldwide citation)

Phenoxycarboxylic acids of the formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, Z and n are as hereinafter set forth, are as described. The compounds of formula I are antagonists of slow reacting substance of anaphylaxis (SRS-A), which renders them useful as agents for the tr ...


5
Matthew Carson, Ronald A Le Mahieu, William C Nason, Jefferson W Tilley: Derivatives of (E)-3-(4-oxo-4H-quinazolin-3-yl)-2-propenamide. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, Matthew Boxer, July 8, 1986: US04599336 (4 worldwide citation)

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, lower cycloalkyl, lower alkoxy, hydroxy, halo, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, di-(C.sub.1 -C.sub.7) alkyl-N(CH.sub.2).sub.n O-- or 2-hydroxyethoxy; n is 2 to 7; R.sub.2 is hydrogen, lower alkyl or ...


6
Matthew Carson, Ronald A LeMahieu, William C Nason: Phenoxycarboxylic acids. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, William G Isgro, November 1, 1988: US04782176 (2 worldwide citation)

Phenoxycarboxylic acids of the formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 R.sub.5, Z and n are as hereinafter set forth, are as described. The compounds of formula I are antagonists of slow reacting substance of anaphylaxis (SRS-A), which renders them useful as agents for the tre ...


7
Matthew Carson, Ronald A LeMahieu, William C Nason: Substituted 4-acetyl-3-hydroxyphenoxy alkanoic acids. Hoffmann La Roche, Jon S Saxe, Bernard S Leon, William G Isgro, December 9, 1986: US04628115 (2 worldwide citation)

The invention relates to compounds of the formula ##STR1## wherein R is hydrogen or lower alkyl, Z is alkylene of 1 to 10 carbon atoms, --(C*H.sub.2).sub.3 --C.tbd.C--, --C*H.sub.2 --C.tbd.C--(CH.sub.2).sub.3 --, and --(CH.sub.2).sub.2 O].sub.n (CH.sub.2).sub.2 -- wherein n is an integer of 1 to 3, ...


8
Amarpreet S Sawhney, Peter K Jarrett, Arthur J Coury, Ronald S Rudowsky, Michelle D Lyman, Luis Z Avila, David J Enscore, Stephen D Goodrich, William C Nason, Fei Yao, Douglas Weaver, Shikha P Barman: Polymerizable biodegradable polymers including carbonate or dioxanone linkages. Genzyme Corporation, Isabelle Blundell, July 3, 2007: USRE039713

Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers are preferably polymerized using fr ...