1
Willem J Kolff, Thomas R Kessler: Peritoneal dialysis catheter. University of Utah, C W Martin, January 22, 1980: US04184497 (134 worldwide citation)

An implantable catheter for subcutaneous placement defining a tubular member which carries an enlarged, hollow, needle-pierceable member on one end thereof. The enlarged hollow member is implanted under the skin. The catheter defines a pair of angled turns, each of the angled turns occupying a plane ...


2
Willem J Kolff: Collapsible artificial ventricle and pumping shell. University of Utah Research Foundation, Thorpe North & Western, February 20, 1990: US04902291 (56 worldwide citation)

An artificial ventricle for use as part of a total artificial heart for implantation within a living being as part of its circulatory system. The ventricle includes a soft and flexible blood pumping sac which can be collapsed to the substantially flattened, squeezed or rolled-up structure of much re ...


3
Willem J Kolff, Yvo M Smulders, Paul D Diegel, James W Long Jr, Donald B Olsen, John W Holfert: Ventricle assist device with volume displacement chamber. University of Utah Research Foundation, Thorpe North & Western, February 1, 1994: US05282849 (35 worldwide citation)

A ventricle assist device for placement within a living body and including a self contained drive motor for generating pumping action with respect to a hydraulic pumping fluid. The ventricle assist device includes a ventricle having a blood chamber and a pumping chamber and an interconnect means cou ...


4
Willem J Kolff: Ventricular assist device and method of manufacture. University of Utah Research Foundation, Workman Nydegger & Jensen, June 13, 1989: US04838889 (34 worldwide citation)

A ventricular assist device and a method of manufacturing the ventricular assist device. The device is generally flat in shape and gently curved so that it may be comfortably implanted under the skin or inside the chest of a patient. The device includes a housing comprising an atrial blood chamber, ...


5
Willem J Kolff: Artificial heart valve made by vacuum forming technique. University of Utah, Workman Nydegger & Jensen, September 25, 1984: US04473423 (31 worldwide citation)

An artificial heart valve having thin, seamless leaflets which converge to the center of a frame from the frame's inner wall. The leaflets each have a convex outflow surface and a concave inflow surface. The leaflets meet along adjacent edges to form cusps. Sinus valsalvae sections of the valve are ...


6
Willem J Kolff, Stephen R Topaz, Peter A Topaz, N Dan Bishop, Dmitry M Golub, Long S Yu, Yvo Smulders, Mark Stegeman, Cornelis Verhoef: Electrohydraulic heart with septum mounted pump. University of Utah Research Foundation, Thorpe North & Western, April 26, 1994: US05306295 (31 worldwide citation)

A total artificial heart for placement inside a living body comprising right and left ventricle enclosures, wherein each ventricle includes an exterior wall formed of (i) contacting wall structure and (ii) noncontacting wall structure which collectively enclose an interior volume comprised of a bloo ...


7
Willem J Kolff, Udipi R Shettigar: Process for therapeutic dissociation of immune complexes and removal of antigens. University of Utah, Workman Nydegger & Jensen, May 5, 1987: US04663049 (24 worldwide citation)

The present invention provides an improved method for treating blood to remove foreign substances such as immune complexes and free antigen. This is advantageously accomplished by separating a portion of a patient's blood as plasma, and acidifying the plasma to a pH below about 3.1 in order to cause ...


8
Willem J Kolff: Vacuum molding technique for manufacturing a ventricular assist device. University of Utah, H Ross Workman, Rick D Nydegger, Dale E Hulse, January 24, 1984: US04427470 (17 worldwide citation)

A ventricular assist device and a method of manufacturing the ventricular assist device. The device is generally flat in shape and gently curved so that it may be comfortably implanted under the skin or inside the chest of a patient. The device includes a housing comprising an atrial blood chamber, ...


9
Willem J Kolff, Stephen R Topaz, N Dan Bishop: Muscle and air powered LVAD. University of Utah Research Foundation, Thorpe North & Western, March 14, 1995: US05397349 (16 worldwide citation)

A method for providing ventricular assist to a patient with a weak or nonfunctional heart includes attaching an artificial ventricle to a patient and pumping said artificial ventricle with a muscle powered hydraulic pump. This method is enhanced by supplementing said artificial ventricle as needed w ...


10
Willem J Kolff: Artificial heart valve made by vacuum forming technique. University of Utah, Workman Nydegger & Jensen, April 16, 1985: US04510628 (11 worldwide citation)

An artifical heart valve having thin, seamless leaflets which converge to the center of a frame from the frame's inner wall. The leaflets each have a convex outflow surface and a concave inflow surface. The leaflets meet along adjacent edges to form cusps. Sinus valsalvae sections of the valve are f ...