1
Wilhelm Bannwarth, Francis Muller: Detection of nucleic acids using a hairpin forming oligonucleotide primer and an energy transfer detection system. Hoffmann La Roche, George M Gould, William H Epstein, Patricia S Rocha Tramaloni, November 12, 1996: US05573906 (140 worldwide citation)

A process for the detection of a nucleic acid sequence in a homogeneous assay format using an energy transfer system is disclosed. This process utilizes a 5' labeled primer containing a selfcomplementary sequence in an amplification or extension process together with a subsequent detection step usin ...


2
Wilhelm Bannwarth, Francis Muller: Ruthenium-lumazine energy transfer systems. Hoffmann La Roche, George M Gould, Dennis P Tramaloni, Patricia S Rocha, January 11, 1994: US05278043 (92 worldwide citation)

Energy-transfer systems which can be used, inter alia, for measuring distances within or between different molecules are described, comprising derivatives of lumazine and ruthenium, in particular derivatives of DNA or RNA sequences.


3
Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous: HIV-2 envelope polypeptides. Roche Diagnostic Systems, George W Johnston, Patricia S Rocha Tramaloni, December 30, 1997: US05702918 (3 worldwide citation)

Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A me ...


4
Wilhelm Bannwarth, Fernand Gerber, Alfred Grieder, Andreas Knierzinger, Klaus Muller, Daniel Obrecht, Arnold Trzeciak: Tri-and tetracyclic compounds. Hoffmann La Roche, George W Johnston, Dennis P Tramaloni, Alan P Kass, September 22, 1998: US05811548 (2 worldwide citation)

There are described compounds of the formula ##STR1## Wherein the variables have been defined herein. The compounds are useful as research tools in the determination of biologically active peptides sequences and also potentially suitable as medicaments, some of them being useful in the prevention or ...


5
Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous: HIV-2 envelope polypeptides. Roche Diagnostic Systems, George W Johnston, Patricia S Rocha Tramaloni, July 14, 1998: US05780038 (2 worldwide citation)

Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A me ...


6
Wilhelm Bannwarth, Fernand Gerber, Alfred Grieder, Andreas Knierzinger, Klaus Muller, Daniel Obrecht, Arnold Trzeciak: Tri- and tetracyclic compounds. Hoffmann La Roche, George W Johnston, Dennis P Tramaloni, Alan P Kass, September 22, 1998: US05811389 (1 worldwide citation)

There are described compounds of the formula ##STR1## Wherein the variables have been defined herein. The compounds are useful as research tools in the determination of biologically active peptides sequences and also potentially suitable as medicaments, some of them being useful in the prevention or ...


7
Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous: HIV-2 envelope polypeptides. Roche Diagnostic Systems, George W Johnson, Patricia S Rocha Tramaloni, February 23, 1999: US05874533

Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A me ...


8
Wilhelm Bannwarth, Fernand Gerber, Alfred Grieder: The present invention is concerned with tri- and tetracyclic compounds. Fhoffmann La Roche, REN ZONGHUA, May 18, 1994: CN93117072

There are described compounds of formula I wherein groups have meanings indicated in the description. Those compounds of formula I in which R2 signifies a residue of -NH-R7, R3 signifies a residue of -CO-R8 and R7 and R8 together signify a residue of an amino acid or a chain of up to 20 amino acid r ...