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Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, drugs containing these compounds and process for their preparation.. Thomae Dr K, October 17, 1990: EP0392317-A2 (78 worldwide citation)

The invention relates to benzimidazoles of the formula in which R1 to R6 are defined as in claim 1, their 1- and 3-isomer mixtures and their acid addition salts, which have useful properties. The novel compounds are in particular angiotensin II antagonists.


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Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazol, medicaments containing them and process for their preparation.. Thomae Dr K, September 9, 1992: EP0502314-A1 (45 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of the 1 and 3 isomers thereof, and the salts thereof, which have valuable properties. The compounds are, in particular, angiotensin antagonists.


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Ries Uwe Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Heterocyclic imidazoles, remedies containing them and processes for their preparation.. Thomae Dr K, February 12, 1992: EP0470543-A1 (17 worldwide citation)

The invention relates to heterocyclic imidazoles of the general formula in which A1 to A4 and R1 to R5 are as defined in Claim 1, their 1- and 3-isomer mixtures, their tautomers, their enantiomers and their acid addition salts, which have useful pharmacological properties. The novel compounds are an ...


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Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Ing, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr Pharm, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation.. Thomae Dr K, August 25, 1993: EP0556789-A2 (7 worldwide citation)

The invention relates to substituted biphenylyl derivatives of the general formula in which Ra to Rc, X and n are defined as in Claim 1, mixtures thereof of positional isomers and salts thereof which have useful properties.


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Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Riess Uwe Dr Dipl Chem, Meel Jacques Van Dr Pharm, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benziimidazoles, pharmaceuticals containing them and process for their preparation.. Thomae Dr K, May 26, 1993: EP0543263-A2 (4 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, and to their salts which have useful properties. The novel compounds are in particular angiotensin antagonists.


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Hauel Norbert Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dipl Chem Dr: Benzimidazoles, process for their preparation and their use as angiotensin-ii antagonists.. Thomae Dr K, February 2, 1994: EP0581166-A1 (2 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, and to 1- and 3-isomer mixtures thereof and the salts thereof which have useful properties. The novel compounds are in particular angiotensin antagonists.


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Mihm Gerhard Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacobus Constantinus, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, medicines containing them and process for their preparation.. Thomae Dr K, November 15, 1995: EP0682021-A1 (1 worldwide citation)

1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, pipe ...


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Ries Uwe Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Imidazo(1,2-a)pyridines as angiotensin-ii-antagonists.. Thomae Dr K, August 18, 1993: EP0555825-A1 (1 worldwide citation)

Die Erfindung betrifft Imidazo[1,2-a]pyridine der allgemeinen Formel in der Ra bis Re wie im Anspruch 1 definiert sind, deren Enantiomere und deren Salze, welche wertvolle Eigenschaften aufweisen. Die neuen Verbindungen stellen insbesondere Angiotensin-Antagonisten dar.


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