1
Mark A Hamm, Louis J Barbato, Robert J Crowley, Wendy Naimark, Hatal Patel: Energetically-controlled delivery of biologically active material from an implanted medical device. Boston Scientific Scimed, Jones Day, September 5, 2006: US07101394 (126 worldwide citation)

A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer comprising a biologically active material and optionally a polymeric material is disposed on the surface of t ...


2
Wendy Naimark, Maria Palasis: Medical device for delivering patches. SciMed Life Systems, Jones Day, May 17, 2005: US06893431 (115 worldwide citation)

The present invention relates to a medical device and method for treating the body tissue of a patient. The present invention is also directed to a method of making the medical device and a method of using the medical device. More particularly, the invention relates to a medical device which is inse ...


3
Robert A Herrmann, Wendy Naimark: Lipid-based nitric oxide donors. SciMed Life Systems, David B Bonham Esq, Mayer Fortkort & Williams PC, August 24, 2004: US06780849 (90 worldwide citation)

Novel nitric-oxide releasing lipid molecules are provided which comprise a lipid molecule selected from (a) phosphoglycerides, (b) lipids having a sphingosine base as a backbone, (c) monoacylglyerols, (d) diacylglycerols, (e) glycosylacylglycerols, wherein the lipid molecole is provided with a nitri ...


4
Wendy Naimark, Maria Palasis, Robbert A Herrmann: Medical device for delivery of a biologically active material to a lumen. SciMed Life Systems, Pennie & Edmonds, October 28, 2003: US06638246 (76 worldwide citation)

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer oating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embod ...


5
Wendy Naimark, Maria Palasis, Robbert A Herrmann: Medical device for delivery of a biologically active material to a lumen. Boston Scientific SciMed, Fish & Richardson P C, August 4, 2009: US07569032 (70 worldwide citation)

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer coating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embo ...


6
Robert A Herrmann, Wendy Naimark: Lipid-based nitric oxide donors. Boston Scientific Scimed, Mayer & Williams PC, David B Bonham, April 13, 2010: US07696247 (67 worldwide citation)

Novel nitric-oxide releasing lipid molecules are provided which comprise a lipid molecule selected from (a) phosphoglycerides, (b) lipids having a sphingosine base as a backbone, (c) monoacylglyerols, (d) diacylglycerols, (e) glycosylacylglycerols, and (f) sterol compounds of the formula: where R is ...


7
Samuel J Epstein, Wendy Naimark: Processes for producing polymer coatings for release of therapeutic agent. SciMed Life Systems, Mayer Fortkort & Williams PC, David B Bonham Esq, August 2, 2005: US06923996 (46 worldwide citation)

A method for furnishing a therapeutic-agent-containing medical device is provided. The method comprises: (a) providing a reactive layer comprising a cross-linking agent on a medical device surface; and (b) subsequently applying a polymer-containing layer, which comprises a polymer and a therapeutic ...


8
Janel L Lanphere, Erin P McKenna, Wendy Naimark, Marcia S Buiser, Stephan P Mangin: Drug delivery particle. Boston Scientific Scimed, Fish & Richardson P C, December 9, 2008: US07462366 (38 worldwide citation)

A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.


9
Toby Freyman, Wendy Naimark, Tim Mickley, Samuel J Epstein: Injection devices that provide reduced outflow of therapeutic agents and methods of delivering therapeutic agents. Boston Scientific Scimed, Kenyon & Kenyon, July 4, 2006: US07070582 (32 worldwide citation)

Injection devices are provided, which reduce potential outflow of therapeutic agents from an injection site. Devices are provided having at least a first lumen containing one or more therapeutic agents and a second lumen containing a second material for injection into tissue. Other devices are provi ...


10
Maria Palasis, Wendy Naimark, Robert E Richard: Medical devices for delivery of therapeutic agents. Boston Scientific Scimed, Mayer & Williams PC, David B Bonham Esq, Keum J Park Esq, February 17, 2009: US07491234 (31 worldwide citation)

The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally comprise (a) a therapeutic agent, more typically, a high-molecular-weight therapeut ...