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Wendy Lee, Gaetan Ladouceur, Jacques Dumas, Roger Smith, Shihong Ying, Gan Wang, Zhi Chen, Qingjie Liu, Holia Hatoum Mokdad: Substituted pyrazolyl urea derivatives useful in the treatment of cancer. Bayer Healthcare, Millen White Zelano & Branigan P C, November 23, 2010: US07838524 (15 worldwide citation)

The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).


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Clint D W Brooks, Teodozyj Kolasa, Wendy Lee, Andrew O Stewart: Oxime derivatives of indole and indene compounds as inhibitors of prostaglandin biosynthesis. Abbott Laboratories, Frank Z Yang, May 12, 1998: US05750558 (13 worldwide citation)

Described herein are compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein L is selected from the group consisting of ##STR2## R.sup.2 is selected from (a) ##STR3## R.sup.3 is selected from optionally substituted phenyl, and optionally substituted pyridyl; Y is ...


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William J Scott, Jacques Dumas, Stephen Boyer, Wendy Lee, Yuanwei Chen, Barton Phillips, Sharad Verma, Jianqing Chen, Zhi Chen, Jianmei Fan, Brian Raudenbush, Aniko Redman, Lin Yi, Qingming Zhu, Lila Adnane: Cyanopyridine derivatives useful in the treatment of cancer and other disorders. Bayer Healthcare, Jessica Monachello, July 7, 2009: US07557129 (9 worldwide citation)

This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.


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Jacques P Dumas, Stephen James Boyer, Teddy Kite Joe, Holia N Hatoum Mokdad, Harold C E Kluender, Wendy Lee, Dhanapalan Nagarathnam, Robert N Sibley, Ning Su: Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity. Bayer Pharmaceuticals Corporation, June 7, 2005: US06903101 (6 worldwide citation)

Substituted and Fused pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1 and R2 may be defined independent s ...


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Wendy Lee, Gaetan Ladouceur, Jacques Dumas, Roger Smith, Shihong Ying, Gan Wang, Zhi Chen, Qingjie Liu, Holia Mokdad: Substituted pyrazolyl urea derivatives useful in the treatment of cancer. Bayer Healthcare, Millen White Zelano & Branigan PC, June 26, 2012: US08207166 (5 worldwide citation)

The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).


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Frank P Dininno, Mark L Greenlee, Thomas A Rano, Wendy Lee: 2-phenanthridinyl carbaphenem antibacterial agent. Merck & Co, David A Muthard, Mark D Daniel, Joseph F DiPrima, August 9, 1994: US05336674 (4 worldwide citation)

The present invention relates to antibacterial agents of the carbapenem class, in which the 2-position sidechain is characterized by a phenanthridine moiety typically having a substituent attached to the nitrogen of the phenanthridine and substituted at other positions by various neutral substituent ...


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Joseph F Dellaria, Anwer Basha, Lawrence A Black, Linda J Chernesky, Wendy Lee: ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase. Abbott Laboratories, Jerry F Janssen, August 29, 1995: US05446062 (4 worldwide citation)

Compounds of the structure ##STR1## where W is selected from ##STR2## where Q is oxygen or sulfur, R.sup.6 and R.sup.7 are hydrogen or alkyl, or R.sup.6 and R.sup.7, together with the nitrogen atoms to which they are attached, define a radical of formula ##STR3## Z is --CH.sub.2 --, oxygen, sulfur, ...