1
Jagadish Sircar, Sunil Kumar K C, Wenbin Ying: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, February 6, 2007: US07173036 (17 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


2
Federico C A Gaeta, Andrew Baird, Jerry Anchin, Wenbin Ying, Robert Florkiewicz, Jagadish Sircar, Sunil Kumar K C: Inhibitors of macrophase migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, August 1, 2006: US07084141 (7 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


3
Yoshiro Niitsu, Victor Knopov, Joseph E Payne, Richard P Witte, Mohammad Ahmadian, Loren A Perelman, Violetta Akopian, Yasunobu Tanaka, Elena Feinstein, Sharon Avkin Nahum, Hagar Kalinski, Igor Mett, Kenjiro Minomi, Wenbin Ying, Yun Liu: Retinoid-liposomes for treating fibrosis. Nitto Denko Corporation, Baker & Hostetler, June 3, 2014: US08741867 (7 worldwide citation)

What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPINH1_45a (SEQ ID ...


4
Federico C A Gaeta, Andrew Baird, Jerry Anchin, Wenbin Ying, Robert Florkiewicz, Jagadish Sircar, Sunil Mumar K C: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, September 12, 2006: US07105519 (6 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


5
Yoshiro Niitsu, Victor Knopov, Joseph E Payne, Richard P Witte, Mohammad Ahmadian, Loren A Perelman, Violetta Akopian, Yasunobu Tanaka, Elena Feinstein, Sharon Avkin Nahum, Hagar Kalinski, Igor Mett, Kenjiro Minomi, Wenbin Ying, Yun Liu: Retinoid-liposomes for enhancing modulation of HSP47 expression. Nitto Denko Corporation, Baker & Hostetler, March 4, 2014: US08664376 (6 worldwide citation)

What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1—2 (SEQ ID NOS: 60 and 127), SERPINH1—45a (SEQ ID ...


6
Federico C A Gaeta, Andrew Baird, Jerry Anchin, Wenbin Ying, Robert Florkiewicz, Jagadish Sircar, Sunil Kumar K C: Method for screening an agent that modulates activity of macrophage migration inhibitory factor. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, April 7, 2009: US07514225 (5 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


7
Yoshiro Niitsu, Victor Knopov, Joseph E Payne, Richard P Witte, Mohammad Ahmadian, Loren A Perelman, Violetta Akopian, Yasunobu Tanaka, Elena Feinstein, Sharon Avkin Nahum, Hagar Kalinski, Igor Mett, Kenjiro Minomi, Wenbin Ying, Yun Liu: Method for treating fibrosis using siRNA and a retinoid-lipid drug carrier. Nitto Denko Corporation, Baker & Hostetler, October 4, 2016: US09456984 (4 worldwide citation)

What is described is a method for treating a fibrotic disease by administering a pharmaceutical composition comprising a drug carrier, which comprises a lipid and a retinoid, and a double-stranded nucleic acid molecule, which comprises an antisense sequence to mRNA encoding human hsp47.


8
Jagadish Sircar, Sunil Kumar K C, Wenbin Ying: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, December 25, 2007: US07312220 (2 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


9
Jagadish Sircar, Sunil Kumar K C, Wenbin Ying: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, December 25, 2007: US07312221 (2 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...


10
Jagadish Sircar, Sunil Kumar K C, Wenbin Ying: Inhibitors of macrophage migration inhibitory factor and methods for identifying the same. Avanir Pharmaceuticals, Knobbe Martens Olson & Bear, June 26, 2007: US07235546 (2 worldwide citation)

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts ...