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Arnon Rosenthal, Mary A Hynes, Weilan Ye: Method of dopaminergic and serotonergic neuron formation from neuroprogenitor cells. Genentech, David A Carpenter, August 21, 2001: US06277820 (20 worldwide citation)

The present invention relates to neuronal formation and methods of treating diseases characterized by abnormalities in the activity of dopaminergic (DA) and serotonergic (5HT) neurons. In particular, the invention relates to a method of forming serotonergic neurons in vitro by contacting neuroprogen ...


2
Wei Ching Liang, Gregory D Plowman, Yan Wu, Weilan Ye: Antibodies. Genentech, Morrison & Foerster, July 5, 2011: US07973138 (9 worldwide citation)

The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising nove ...


3
Anan Chuntharapai, Gregory D Plowman, Marc Tessier Lavigne, Yan Wu, Weilan Ye: Anti-alpha5/beta1 antibody. Genentech, Morrison & Foerster, January 8, 2013: US08350010 (3 worldwide citation)

The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 ...


4
Kevin P Baker, Napoleone Ferrara, Hanspeter Gerber, Mary E Gerritsen, Audrey Goddard, Paul J Godowski, Austin L Gurney, Kenneth J Hillan, Scot A Marsters, James Pan, Jean Philippe F Stephan, Colin K Watanabe, P Mickey Williams, William I Wood, Weilan Ye: PRO20044 nucleic acids. Genentech, Elizabeth M Barnes, Mark T Kresnak, Ginger R Dreger, November 14, 2006: US07135334 (3 worldwide citation)

Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be dia ...


5
Wei Ching Liang, Gregory D Plowman, Yan Wu, Weilan Ye: Antibodies. Genentech, Morrison & Foerster, September 23, 2014: US08840887 (1 worldwide citation)

The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising nov ...


6
Wei Ching Liang, Gregory D Plowman, Yan Wu, Weilan Ye: Anti-α5β1 antibodies and uses thereof. Genentech, Morrison & Foerster, February 24, 2015: US08962275 (1 worldwide citation)

The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.


7
Wei Ching Liang, Gregory D Plowman, Yan Wu, Weilan Ye: Anti- α5 β1 antibodies and uses thereof. Genentech, Carol A Fang, February 28, 2012: US08124740 (1 worldwide citation)

The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.


8
Weilan Ye, Maike Schmidt, Jo Anne Hongo, Yan Wu: Antibodies to EGFL7 and methods for their use. Genentech, Clark & Elbing, Karen L Elbing, March 19, 2013: US08398976 (1 worldwide citation)

The invention provides anti-EGFL7 antibodies, and compositions comprising and methods of using these antibodies.


9
Yan Wu, Weilan Ye, Jeremy Bryant Burton, Cecilia Chiu: Anti-LRP5 antibodies and methods of use. Genentech, Frank Jn Berendt, December 20, 2016: US09522954 (1 worldwide citation)

The invention provides anti-LRP5 antibodies and methods of making and using the same.


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