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Chakravarty Prasun K, Greenlee William J, Mantlo Nathan B, Patchett Arthur A, Walsh Thomas F: Substituted imidazo-fused 6-membered heterocycles as angiotensin ii antagonists.. Merck & Co, December 5, 1990: EP0400974-A2 (191 worldwide citation)

Substituted Imidazo-fused 6-membered heterocycles of structural formula: wherein A, B, C, and D are independently carbon atoms or nitrogen atoms are angiotensin II antagonists useful in the treatment of hypertension and congestive heart failure.


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Chakravarty Prasun K, Patchett Arthur A, Camara Valerie J, Walsh Thomas F, Greenlee William J: Substituted benzimidazoles as angiotensin ii antagonists.. Merck & Co, December 5, 1990: EP0400835-A1 (113 worldwide citation)

There are disclosed new substituted benzimidazole compounds and derivatives thereof which are useful as angiotensin II antagonists. These compounds have the general formula: l


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Chakravarty Prasun K, Patchett Arthur A, Schoen William, Greenlee William J, Mantlo Nathan B, Walsh Thomas F: Angiotensin ii antagonists.. Merck & Co, December 5, 1990: EP0401030-A2 (53 worldwide citation)

Novel substituted imidazo-fused 7-member ring heterocycles of the formulae (I) and (Ia), which are useful as angiotensin II antagonists, are disclosed. -


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Allen Eric E, Greenlee William J, Patchett Arthur A, Walsh Thomas F, Chakravarty Prasun K: Substituted pyrimidinones as angiotensin ii antagonists.. Merck & Co, March 27, 1991: EP0419048-A2 (46 worldwide citation)

Novel substituted pyrimidinones of formula (I) which are useful as angiotensin II antagonists, are disclosed. h


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Chang Linda L, Ashton Wallace T, Maccoss Malcolm, Chakravarty Prasun K, Greenlee William J, Patchett Arthur A, Walsh Thomas F: Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin ii antagonists.. Merck & Co, February 13, 1991: EP0412594-A2 (44 worldwide citation)

There are disclosed new substituted triazolinone, triazolinethione, and triazolinimine compounds which are useful as angiotensin II antagonists. These compounds have the general formula: t


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Greenlee William J, Johnston David B R, Maccoss Malcolm, Mantlo Nathan B, Patchett Arthur A, Chakravarty Prasun K, Walsh Thomas F: Substituted imidazo-fused 5-membered ring heterocycles as angiotensin ii antagonists.. Merck & Co, January 9, 1991: EP0407102-A1 (37 worldwide citation)

There are disclosed new substituted imidazo-fused 5-membered ring heterocyclic compounds and derivatives thereof which are useful as angiotensin II antagonists. These compounds have the general formula:


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Greenlee William J, Walsh Thomas F, Pettibone Douglas J, Tata James R, Rivero Ralph A, Williams David L, Bagley Scott W, Dhanoa Daljit S, Chakravarty Prasun K, Fitch Kenneth J, Broten Theodore P, Kevin Nancy Jo: Phenoxyphenylacetic acid derivatives.. Merck & Co, September 28, 1994: EP0617001-A1 (32 worldwide citation)

Phenoxyphenylacetic acids and derivatives of the general structural formula I have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, b ...