1
W Cameron Black, Chun Sing Li, Daniel Guay, Petpiboon Prasit, Patrick Roy: Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase. Merck Frosst Canada, Curtis C Panzer, David L Rose, April 25, 1995: US05409944 (113 worldwide citation)

Disclosed are compounds of Formula I useful in the treatment of cyclooxygenase mediated diseases such as pain, fever and inflammation of a variety of conditions including rheumatic fever, symptoms associated with influenza or other viral infections, common cold, low back and neck pain, dysmenorrhea, ...


2
Petpihoon Prasit, Christopher Ian Bayly, Joel Stephane Robichaud, W Cameron Black, Eduardo L Setti, Robert M Rydzewski, James T Palmer: Cathepsin cysteine protease inhibitors. Merck & Co, Axys Pharmaceuticals, Nicole M Beeler, Mark R Dāniel, March 14, 2006: US07012075 (14 worldwide citation)

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.


3
Petpihoon Prasit, Christopher Ian Bayly, Joel Stephane Robichaud, W Cameron Black, Eduardo L Setti, Robert M Rydzewski, James T Palmer: Cathepsin cysteine protease inhibitors. Merck And Co, October 7, 2004: US20040198982-A1

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.