1
Michael Lebl, Vit Pokorny, Viktor Krchnak: Apparatus and method for combinatorial chemistry synthesis. Trega Biosciences, Pennie & Edmonds, April 4, 2000: US06045755 (115 worldwide citation)

In a first embodiment, this invention includes an integrated robot apparatus for performing combinatorial chemistry synthesis protocols and having interchangeable work-stations, robot arm tools, and reaction vessels and reaction vessel arrays. The work-stations and tools are specialized to perform t ...


2
Michal Lebl, Jutta Eichler, Vit Pokorny, Jiri Jehnicka, Petr Mudra, Karel Zenisek, Alena Stierandova, Jan Kalousek, Jan Bolf: Method of performing multiple synthesis of peptides on solid carrier. Ceskoslovenska akademie ved, Dressler Goldsmith Shore Sutker & Milnamow, April 13, 1993: US05202418 (42 worldwide citation)

The invention relates to a method and apparatus for performing a multiple synthesis of peptides on a solid carrier. Active components are successively bonded to functional groups anchored on a carrier. The carrier planar functionalized porous material divided into compartments, into which the needed ...


3
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Illumina, Dorsey & Whitney, December 16, 2003: US06663832 (38 worldwide citation)

An apparatus for high-throughput combinatorial syntheses of organic molecules including a reaction vessel for containing a combinatorial-chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


4
Michal Lebl, Jutta Eichler, Vit Pokorny, Jiri Jehnicka, Petr Mudra, Karel Zenisek, Alena Stierandova, Jan Kalousek, Jan Bolf: Apparatus for making multiple synthesis of peptides on solid support. Academy of Sciences of the Czech Republic, Dressler Goldsmith Shore & Milnamow, August 30, 1994: US05342585 (33 worldwide citation)

An apparatus is disclosed for performing a multiple synthesis of peptides on a solid carrier. Active components are successively bonded to functional groups anchored on a carrier. The carrier comprises a planar porous material divided into functionalized compartments, into which an active component ...


5
Michal Lebl, Jutta Eichler, Vit Pokorny, Jifi Jehnicka, Petr Mudra, Karel Zenisek, Alena Stierandova, Jan Kalousek, Jan Bolf: Method of making multiple synthesis of peptides on solid support. Academy of Sciences of the Czech Republic changed from Ceskoslovenska akademie ved, Dressler Goldsmith Shore & Milnamow, August 16, 1994: US05338831 (31 worldwide citation)

A method is disclosed for performing a multiple synthesis of peptides on a solid carrier. Active components are successively bonded to functional groups anchored on a carrier. The carrier is a planar porous material divided into functionalized compartments, into which an active component is put, via ...


6
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Illumina, Knobbe Martens Olson & Bear, June 18, 2013: US08465694 (1 worldwide citation)

An apparatus for high-throughput combinatorial synthesis of organic molecules including a reaction vessel for containing a combinatorial chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


7
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Flehr Hohbach Test Albritton & Herbert, March 7, 2002: US20020028159-A1

An apparatus for high-throughput combinatorial syntheses of organic molecules including a reaction vessel for containing a combinatorial-chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


8
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Flehr Hohbach Test Albritton & Herbert, April 18, 2002: US20020044894-A1

An apparatus for high-throughput combinatorial syntheses of organic molecules including a reaction vessel for containing a combinatorial-chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


9
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. June 16, 2011: US20110143965-A1

An apparatus for high-throughput combinatorial synthesis of organic molecules including a reaction vessel for containing a combinatorial chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


10
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Knobbe Martens Olson & Bear, January 22, 2009: US20090023605-A1

An apparatus for high-throughput combinatorial synthesis of organic molecules including a reaction vessel for containing a combinatorial chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...