1
Thomas Beckert, Hans Ulrich Petereit, Vishal K Gupta: Multilayer pharmaceutical product for release in the colon. Roehm & Co KG, Oblon Spivak McClelland Maier & Neustadt P C, October 14, 2003: US06632454 (17 worldwide citation)

The invention relates to the use of a multilayer pharmaceutical product that substantially comprises a) a core containing a pharmaceutically active substance, b) an inner coating consisting of a copolymer or a mixture of copolymers that are composed of 85 to 98 wt.- % of radically polymerized C1 to ...


2
Jae Han Park, Tiffani Eisenhauer, Anish Dhanarajan, Vishal K Gupta, Stephen Overholt: Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans. Mallinckrodt, Mayer Brown, December 3, 2013: US08597681 (15 worldwide citation)

Methods for producing stabilized solid dosage form pharmaceutical compositions are provided. In particular, methods for preparing protected granules containing morphinans, and solid dosage form pharmaceutical compositions produced using the morphinan-protected granules are provided.


3
Krishna Devarakonda, Michael J Giuliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia. Mallinckrodt, Mayer Brown, October 14, 2014: US08858963 (11 worldwide citation)

The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen- ...


4
Krishna Devarakonda, Michael J Guiliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia. Mallinckrodt, Mayer Brown, February 25, 2014: US08658631 (8 worldwide citation)

The present disclosure provides an extended release pharmaceutical composition comprising oxycodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-in ...


5
Krishna Devarakonda, Michael J Giuliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia. MALLINCKRODT, Mayer Brown, June 9, 2015: US09050335 (5 worldwide citation)

The present disclosure provides extended release pharmaceutical compositions comprising oxycodone and acetaminophen that produce a quick initial onset of analgesia, yet, maintain analgesia for about 12 hours after administration of the composition to a subject in need thereof. The pharmaceutical com ...


6
Krishna Devarakonda, Michael J Guiliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Gastric retentive extended release pharmaceutical compositions. Mallinckrodt, Mayer Brown, June 3, 2014: US08741885 (5 worldwide citation)

The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and releas ...


7
Krishna R Devarakonda, Michael J Giuliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Gastric retentive extended release pharmaceutical compositions. Mallinckrodt, Mayer Brown, July 29, 2014: US08790694 (5 worldwide citation)

The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and releas ...


8
Krishna R Devarakonda, Michael J Giuliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia. Mallinckrodt, Mayer Brown, March 31, 2015: US08992975 (5 worldwide citation)

The present disclosure provides an extended release pharmaceutical composition comprising oxycodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-in ...


9
Krishna R Devarakonda, Michael J Giuliani, Vishal K Gupta, Ralph A Heasley, Susan Shelby: Gastric retentive extended release pharmaceutical compositions. MALLINCKRODT, Mayer Brown, September 6, 2016: US09433582 (1 worldwide citation)

The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and releas ...


10
Jae Han Park, Tiffani Eisenhauer, Anish Dhanarajan, Vishal K Gupta, Stephen Overholt: Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans. MALLINCKRODT, Mayer Brown, December 1, 2015: US09198861 (1 worldwide citation)

Methods for producing stabilized solid dosage form pharmaceutical compositions are provided. In particular, methods for preparing protected granules containing morphinans, and solid dosage form pharmaceutical compositions produced using the morphinan-protected granules are provided.