1
Peter C Simpson, James R Petisce, Victoria Carr Brendel, James H Brauker: Electrode systems for electrochemical sensors. DexCom, Knobbe Martens Olson & Bear, July 11, 2006: US07074307 (719 worldwide citation)

The present invention relates generally to systems and methods for improved electrochemical measurement of analytes. The preferred embodiments employ electrode systems including an analyte-measuring electrode for measuring the analyte or the product of an enzyme reaction with the analyte and an auxi ...


2
James H Brauker, Victoria Carr Brendel, Paul V Neale, Laura A Martinson, Mark A Tapsak: Optimized sensor geometry for an implantable glucose sensor. DexCom, Knobbe Martens Olson & Bear, November 14, 2006: US07134999 (715 worldwide citation)

An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a curved portion of the body such tha ...


3
Peter C Simpson, Paul Goode, Mark A Tapsak, Victoria Carr Brendel: Electrochemical sensors including electrode systems with increased oxygen generation. DexCom, Knobbe Martens Olson & Bear, September 19, 2006: US07108778 (639 worldwide citation)

The present invention relates generally to systems and methods for increasing oxygen generation in electrochemical sensors in order to overcome the oxygen limitations. The preferred embodiments employ electrode systems with at least two electrodes in relatively close proximity to each other; wherein ...


4
James H Brauker, Victoria Carr Brendel, Mark A Tapsak: Porous membranes for use with implantable devices. DexCom, Knobbe Martens Olson & Bear, March 20, 2007: US07192450 (638 worldwide citation)

A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain that is resistant to cellular atta ...


5
Peter Simpson, James Brauker, Victoria Carr Brendel, Paul Goode, Mark Tapsak: Systems and methods for improving electrochemical analyte sensors. DexCom, Knobbe Martens Olson & Bear, July 25, 2006: US07081195 (480 worldwide citation)

An analyte-measuring device, particularly an electrochemical sensor, is provided for measuring current values at multiple bias potential settings to assess the quality of the analyte measurement, identify interference in the signal, and calculate substantially interference-free analyte concentration ...


6
Paul V Goode Jr, James H Brauker, Apurv U Kamath, Victoria Carr Brendel: System and methods for processing analyte sensor data. DexCom, Knobbe Martens Olson & Bear, October 6, 2009: US07599726 (475 worldwide citation)

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated o ...


7
Paul V Goode Jr, James H Brauker, Apurv U Kamath, Victoria Carr Brendel: System and methods for processing analyte sensor data. DexCom, Knobbe Martens Olson & Bear, September 1, 2009: US07583990 (473 worldwide citation)

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated o ...


8
James Petisce, Mark A Tapsak, Peter C Simpson, Victoria Carr Brendel, James H Brauker: Oxygen enhancing membrane systems for implantable devices. DexCom, Knobbe Martens Olson & Bear, May 27, 2008: US07379765 (392 worldwide citation)

The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic rea ...


9
Victoria Carr Brendel, Peter C Simpson, James H Brauker: Biointerface membrane with macro-and micro-architecture. DexCom, Knobbe Martens Olson & Bear, April 29, 2008: US07364592 (383 worldwide citation)

Disclosed herein are biointerface membranes including a macro-architecture and a micro-architecture co-continuous with and bonded to and/or located within at least a portion of the macro-architecture. The macro- and micro-architectures work together to manage and manipulate the high-level tissue org ...


10
Paul V Goode Jr, James H Brauker, Apurv U Kamath, Victoria Carr Brendel: System and methods for processing analyte sensor data. DexCom, Knobbe Martens Olson & Bear, March 29, 2011: US07914450 (213 worldwide citation)

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated o ...