1
Mertelsmann Roland, Welte Karl, Venuta Salvatore: Purification of interleukin 2.. Sloan Kettering Inst Cancer, October 26, 1983: EP0092163-A2 (35 worldwide citation)

Interleukin 2 (IL 2; T-cell growth factor), produced with and without costimulation by Burkitt's lymphoma line Daudi, is purified approximately 37,000-fold to apparent homogeneity from lymphocyte-conditioned medium by (NH4)2SO4- precipitation, ion-exchange chromatography, gel filtration and hydropho ...


2
Savino Rocco, Tassone Pierfrancesco, Venuta Salvatore: Combination of interleukin-6 antagonists and antiproliferative drugs. Universita Degli Studi Magna Graecia Di Catanzaro, Savino Rocco, Tassone Pierfrancesco, Venuta Salvatore, SPADARO Marco, September 14, 2006: WO/2006/094971 (1 worldwide citation)

The combination of an interleukin-6 (IL-6) antagonist and an antiproliferative drug is described. In its preferred embodiment, the present invention describes the combination of an IL-6 superantagonist, particularly a superantagonist totally incapable of binding gpl30 and an antiproliferative drug b ...


3
Bisogni Rita, Lamberti Annalisa, Petrella Antonello, Romano Maria Fiammetta, Turco Maria Caterina, Venuta Salvatore: (s) Encoded by such nucleotides for modulation of apoptosis. Univ Napoli, Uni Degli Studi Di Catanzaro M, October 8, 2003: EP1349872-A2

It is described a nucleotide sequence and a corresponding protein for which a role and utility in the regulation of programmed cell death or apoptosis are defined. Applications and uses of the sequence and corresponding protein concern all the physiologic and pathologic processes that involve cell d ...


4
Savino Rocco, Tassone Pierfrancesco, Venuta Salvatore: Combination of interleukin-6 antagonists and antiproliferative drugs. Uni Degli Studi Di Catanzaro M, December 12, 2007: EP1863533-A1

The combination of an interleukin-6 (IL-6) antagonist and an antiproliferative drug is described. In its preferred embodiment, the present invention describes the combination of an IL-6 superantagonist, particularly a superantagonist totally incapable of binding gpl30 and an antiproliferative drug b ...


5
Bisogni Rita, Lamberti Annalisa, Petrella Antonello, Romano Maria Fiammetta, Turco Maria Caterina, Venuta Salvatore: (s) Encoded by such nucleotides for modulation of apoptosis. Universita Degli Studi Di Napoli Federico Ii, Universita Degli Studi Di Catanzaro Magna Graecia, Bisogni Rita, Lamberti Annalisa, Petrella Antonello, Romano Maria Fiammetta, Turco Maria Caterina, Venuta Salvatore, sGERVASI Gemma, July 18, 2002: WO/2002/055553

It is described a nucleotide sequence and a corresponding protein for which a role and utility in the regulation of programmed cell death or apoptosis are defined. Applications and uses of the sequence and corresponding protein concern all the physiologic and pathologic processes that involve cell d ...