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Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, drugs containing these compounds and process for their preparation.. Thomae Dr K, October 17, 1990: EP0392317-A2 (78 worldwide citation)

The invention relates to benzimidazoles of the formula in which R1 to R6 are defined as in claim 1, their 1- and 3-isomer mixtures and their acid addition salts, which have useful properties. The novel compounds are in particular angiotensin II antagonists.


2
Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazol, medicaments containing them and process for their preparation.. Thomae Dr K, September 9, 1992: EP0502314-A1 (45 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of the 1 and 3 isomers thereof, and the salts thereof, which have valuable properties. The compounds are, in particular, angiotensin antagonists.


3
Narr Berthold Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr, Entzeroth Michael Dr, Ries Uwe Dr: Benzimidazoles, medicaments containing them and process for their preparation.. Thomae Dr K, January 29, 1992: EP0468470-A1 (31 worldwide citation)

The invention relates to benzimidazoles of the general formula in which R1 to R4 are as defined in Claim 1, mixtures of their 1-, 3-isomers, and their salts, which have valuable properties. The novel compounds are, in particular, angiotensin antagonists.


4
Mueller Erich Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: 2-aryl imidazoles, pharmaceutical compositions containing them and process for their preparation.. Thomae Dr K, January 28, 1987: EP0209707-A2 (29 worldwide citation)

2-Arylimidazoles of the formula in which R denotes a hydrogen atom or an alkyl group, Ar denotes a group of the formula A and B together with the two carbon atoms in between denote a group of the formula in which R1 denotes an alkylsulphenyl, alkylsulphinyl, alkylsulphonyl or alkylsulphoximino group ...


5
Heider Joachim Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Austel Volkhard Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: Imidazo derivatives, their preparation and medicines containing them. Thomae Dr K, June 25, 1986: EP0185345-A1 (21 worldwide citation)

Die Erfindung betrifft neue Imidazoderivate der allgemeinen Formel in der keiner, ein oder zwei der Reste A, B, C oder D ein Stickstoffatom, ein weiterer der Reste A, B, C oder D eine gegebenenfalls durch ein Halogenatom, eine Alkylmercapto-, Alkylsulfonyloxy-, Amino-, Alkylamino-, Dialkylamino- ode ...


6
Ries Uwe Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Heterocyclic imidazoles, remedies containing them and processes for their preparation.. Thomae Dr K, February 12, 1992: EP0470543-A1 (17 worldwide citation)

The invention relates to heterocyclic imidazoles of the general formula in which A1 to A4 and R1 to R5 are as defined in Claim 1, their 1- and 3-isomer mixtures, their tautomers, their enantiomers and their acid addition salts, which have useful pharmacological properties. The novel compounds are an ...


7
Heider Joachim Dr Dipl Chem, Austel Volkhard Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Van Meel Jacques Dr, Diederen Willi Dr: Imidazo derivatives, their preparation and medicaments containing these compounds.. Thomae Dr K, June 25, 1986: EP0185346-A2 (12 worldwide citation)

Imidazo derivatives of the formula in which one or two of the radicals A, B, C or D represent a nitrogen atom, another of the radicals A, B, C or D represents a hydroxymethine group and the remainder of the radicals A, B, C or D represent methine groups, where one of these methine groups, if it is n ...


8
Hauel Norbert Dr Dipl Chem, Mauz Annerose Dr Dipl Biol, Van Meel Jacques Dr, Entzeroth Michael Dr Dipl Chem, Zimmermann Rainer Dr Dipl Bioc, Diederen Willi Dr: 2-hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them.. Thomae Dr K, December 5, 1990: EP0400519-A1 (10 worldwide citation)

Die Erfindung betrifft neue 2-Hydroxy-n-propylamine der Formel R1-O-CH2-CHOH-CH2-NH-A-R2 ,(I) in der R1,R2 und A wie im Anspruch 1 definiert sind, deren Tautomere, deren Enantiomere und deren Säureadditionssalze, insbesondere für die pharmazeutische Anwendung deren physiologisch verträglichen Säurea ...


9
Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Ing, Ries Uwe Dr Dipl Chem, Van Meel Jacques Dr Pharm, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation.. Thomae Dr K, August 25, 1993: EP0556789-A2 (7 worldwide citation)

The invention relates to substituted biphenylyl derivatives of the general formula in which Ra to Rc, X and n are defined as in Claim 1, mixtures thereof of positional isomers and salts thereof which have useful properties.


10
Hauel Norbert Dr Dipl Chem, Narr Berthold Dr Dipl Chem, Noll Klaus Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Heider Joachim Dr Dipl Chem, Psiorz Manfred Dr Dipl Chem, Diederen Willi Dr, Van Meel Jacques Dr: Pyridazinones, their preparation and pharmaceutical compositions containing them.. Thomae Dr K, October 1, 1986: EP0196005-A1 (7 worldwide citation)

1. Pyridazinones of general formula I see diagramm : EP0196005,P30,F1 wherein X represents an oxygen or sulphur atom, R1 represents a saturated 5- to 7-membered alkyleneimino ring bonded via a nitrogen atom or a 5- to 7-membered saturated imino, N-alkylimino, N-phenylalkylimino, N-alkanoylimino or N ...



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