1
Van Antwerp William P: Polyurethane/polyurea compositions containing silicone for biosensor membranes. Minimed, January 14, 1998: EP0817809-A1 (391 worldwide citation)

Biocompatible membranes for use with biosensors are provided. The membranes are polymers which can be prepared from (a) a diisocyanate, (b) a hydrophilic polymer, (c) a siloxane polymer having functional groups at the chain termini, and optionally, (d) a chain extender.


2
Lord Peter C, Van Antwerp William P, Mastrototaro John J, Cheney Ii Paul S, Schnabel Nannette M: Transcutaneous sensor insertion set.. Minimed, October 25, 1995: EP0678308-A1 (76 worldwide citation)

An insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a slotted insertion needle extending through a mounting base adapted for mounting onto the patient's skin. A flexible thin film ...


3
Lord Peter C, Van Antwerp William P, Mastrototaro John J, Cheney Paul S Ii, Schnabel Nannette M: Dispositif dinsertion dune sonde percutanee, Transcutaneous sensor insertion set. Minimed, Medtronic Minimed, GOWLING LAFLEUR HENDERSON, July 26, 2005: CA2143172 (59 worldwide citation)

An insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a slotted insertion needle extending through a mounting base adapted for mounting onto the patient's skin. A flexible thin film ...


4
Cheney Ii Paul S, Van Antwerp William P: Method of fabricating thin film sensors.. Minimed, October 18, 1995: EP0677743-A2 (16 worldwide citation)

Thin film electrochemical sensor (10) is made by applying curable adhesive (30) in a closed loop pattern to a flat surface (28) of a rigid substrate (12), assembling an insulative sheet base layer (16) over the substrate and adhesive so that the adhesive is at its perimeter and a shallow cavity (32) ...


5
Steil Garry M, Rebrin Kerstin, Goode Paul V Jr, Mastrototaro John J, Purvis Richard E, Van Antwerp William P, Shin John J, Talbot Cary D: Closed loop system for controlling insulin infusion. Minimed, March 13, 2002: EP1185321-A1 (14 worldwide citation)

A closed loop infusion system controls the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signa ...


6
Van Antwerp William P, Karre Sheana, Prokop Adrian, Stinson Sara Akiko, Fong Jason, Rosenberg James J: Method for circuit protection during radiation sterilization. Minimed, February 13, 2002: EP1178841-A2 (5 worldwide citation)

A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetically coupled to the support substrate to seal t ...


7
Van Antwerp William P, Moberg Sheldon B: Infusion site leak detection system. Minimed, December 11, 2002: EP1263488-A2 (1 worldwide citation)

An infusion leak detection system indicates that a fluid to be delivered into an individual's body has leaked near an infusion site. The infusion site is at a location where a delivery element, such as a cannula, needle, or the like, penetrates an individual's body. Preferably, one end of the delive ...


8
Van Antwerp William P, Hamlen Robert C, Grovender Eric A: Pharmacokinetic and pharmacodynamic tools to define patient specific therapeutic regimens. Medtronic, Van Antwerp William P, Hamlen Robert C, Grovender Eric A, WOOD William J, October 1, 2009: WO/2009/120991 (1 worldwide citation)

Methods for treating Hepatitis infections are provided. In one embodiment, an initial dosage of interferon is administered to a patient, and interferon serum levels and viral load data is collected over time. This data can be used to determine patient- specific pharmacokinetic and pharmacodynamic pa ...


9
Holker James D, Calle Guillermo A, Branch Kevin D, Mastrototaro John J, Van Antwerp William P, Van Antwerp Nannette: Improved analyte sensor. Medtronic Minimed, October 13, 2005: JP2005-279285 (1 worldwide citation)

PROBLEM TO BE SOLVED: To provide an improved analyte sensor assembly including a sensor and a slotted needle with a slot.SOLUTION: A sensor (400) and method of making the same for implantation in a body that includes a substrate (402) with notches cut in the substrate to form a necked down region (4 ...


10
Mann Alfred E, Habib Magdi F, Mcconnell Susan M, Van Antwerp William P, Lord Peter C: Inlet port for a medication infusion pump. Minimed, May 10, 2000: EP0998317-A1

A medication infusion pump (10) is provided for substantially constant flow delivery of medication from medication chamber (12) through catheter (16) to a patient. The pump (10) comprises compact housing (18) adapted for implantation into the body of a patient, wherein housing (18) defines a hollow ...