1
Stéphane De Lombaert
BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M: INHIBITEURS OXADIAZOLE DE PRODUCTION DE LEUCOTRIÈNES, OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M, MORRIS Michael P, March 29, 2012: WO/2012/040137

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases an ...


2

3

4

5

6

7

8
TREU Matthias, ZAHN Stephan Karl, AMOUZEGH Patricia, LECCI Cristina, TYE Heather: OXINDOLEPYRIMIDINES UTILISÉES EN TANT QUINHIBITEURS DU RÉCEPTEUR IGF-1R, OXINDOLOPYRIMIDINE AS IGF1R RECEPTOR INHIBITORS. BOEHRINGER INGELHEIM INTERNATIONAL, TREU Matthias, ZAHN Stephan Karl, AMOUZEGH Patricia, LECCI Cristina, TYE Heather, HAMMANN Heinz, June 28, 2012: WO/2012/085126

The present invention encompasses compounds of general formula (I) wherein the groups R5 to R10, A, L1, B, m and p are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain such com ...


9

10