1
Wenge Xie, Brian Herbert, Jianguo Ma, Truc Minh Nguyen, Richard Schumacher, Carla Maria Gauss, Ashok Tehim: Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano & Branigan P C, March 8, 2011: US07902217 (21 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Furthe ...


2
Wenge Xie, Brian Herbert, Jianguo Ma, Truc Minh Nguyen, Richard Schumacher, Carla Maria Gauss, Ashok Tehim: Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof. Memory Pharmaceutical Corporation, Millen White Zelano Branigan P C, February 10, 2009: US07488737 (18 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Furthe ...


3
Wenge Xie, Brian Herbert, Jianguo Ma, Truc Minh Nguyen, Richard Schumacher, Carla Maria Gauss, Ashok Tehim: Indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano Branigan P C, July 8, 2008: US07396833 (13 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention ...


4
Robert Dunn, Truc Minh Nguyen, Wenge Xie, Ashok Tehim: Compounds having 5-HT6 receptor affinity. Memory Pharmaceuticals Corporation, Darby & Darby P C, Lydia G Olson, April 13, 2010: US07696229 (6 worldwide citation)

The present disclosure provides compounds having affinity for the 5HT6 receptor which are of the formula (I): wherein R1-R3 A, B, D, E, G, Q, and x are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use th ...


5
Brian Herbert, Wenge Xie, Truc Minh Nguyen, Allen T Hopper, Ashok Tehim: Heterocyclic compounds, methods for the preparation thereof, and uses thereof. Memory Pharmaceuticals, Millen White Zelano & Branigan P C, July 17, 2007: US07244745 (4 worldwide citation)

The compounds of the present invention are of formula I: wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.


6
Truc Minh Nguyen, Wenge Xie, Richard Schumacher, Brian Herbert, Ashok Tehim: Nicotinic alpha-7 receptor ligands and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano Branigan P C, December 1, 2009: US07625924 (3 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention ...


7
Wenge Xie, Brian Herbert, Richard A Schumacher, Truc Minh Nguyen, Jianguo Ma, Carla Maria Gauss, Ashok Tehim: Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof. Memory Pharmaceuticals Corporation, Millen White Zelano & Branigan P C, July 16, 2013: US08486937 (2 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Furthe ...


8
Wenge Xie, Brian Herbert, Richard A Schumacher, Truc Minh Nguyen, Jianguo Ma, Carla Maria Gauss, Ashok Tehim: Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano & Branigan P C, September 11, 2012: US08263619 (2 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Furthe ...


9
Wenge Xie, Brian Herbert, Richard A Schumacher, Jianguo Ma, Truc Minh Nguyen, Carla Maria Gauss, Ashok Tehim: 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano Branigan P C, December 15, 2009: US07632831 (1 worldwide citation)

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention ...


10
Wenge Xie, Brian Herbert, Jianguo Ma, Truc Minh Nguyen, Richard Schumacher, Carla Maria Gauss, Ashok Tehim: Indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof. Memory Pharmaceuticals Corporation, Millen White Zelano & Branigan P C, June 21, 2011: US07964600

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention ...