1
Toshinobu Uemura, Toshiaki Okhuma, Kiyohide Shinooka, Hiroshi Ishikuro, Yoshio Ueda: Novel drug carrier and pharmaceutical preparation comprising the same. Fujisawa Pharmaceutical, Oblon Fisher Spivak McClelland & Maier, September 1, 1987: US04690822 (78 worldwide citation)

The invention relates to a pharmaceutical oral capsule preparation filled with a substantially anhydrous mixture which is in solid or semi-solid form comprising:


2
Minoru Nakano, Toshinobu Uemura, Shinichi Morizane, Kiyoshi Okuda, Keiko Nakata: Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, August 23, 1994: US05340591 (60 worldwide citation)

A solid dispersion and a method of producing a solid dispersion of a sparingly water-soluble drug characterized by mixing the sparingly water-soluble drug and a water-soluble polymer at a temperature where neither the water-soluble drug nor water-soluble polymer is melted.


3
Toshinobu Uemura, Kiyohide Shinooka, Tokuaki Kajiho: Sustained release tablet. Fujisawa Pharmaceutical, Oblon Fisher Spivak McClelland & Maier, September 22, 1987: US04695467 (52 worldwide citation)

The invention relates to a sustained release tablet which comprises easily disintegrable granules containing


4
Toshinobu Uemura, Keiji Kai, Masateru Kodani, Fumiyo Yoshida, Matsuhiko Aratani: .alpha.-crystals of cefazolin sodium. Fujisawa Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, February 6, 1990: US04898937 (1 worldwide citation)

This invention relates to .alpha.-crystals of cefazolin sodium with a water content in the range of 13.0 to 15.8%, useful as an antibiotic of improved thermal and light stability.


5
Shunji Uramatsu, Akane Kida, Hitoshi Shinike, Toshinobu Uemura, Yoshinobu Fukumori: Base for dry solid dispersion, solid dispersion containing the base, and composition containing the dispersion. Daido Chemical Corporation, Nisshin Kasei, Locke Lord, James E Armstrong IV, Nicholas J DiCeglie Jr, August 11, 2015: US09101617

The present invention provides a novel base material for a dry solid dispersion, a solid dispersion containing the base material, and a composition containing the dispersion; the solid dispersion of the present invention, which contains a poorly soluble component with improved dissolvability, can be ...


6
Shunji Uramatsu, Akane Kida, Hitoshi Shinike, Toshinobu Uemura, Yoshinobu Fukumori: Novel base for dry solid dispersion, solid dispersion containing the base, and composition containing the dispersion. Daido Chemical Corporation, Edwards Angell Palmer & Dodge, May 13, 2010: US20100120924-A1

The present invention provides a novel base material for a dry solid dispersion, a solid dispersion containing the base material, and a composition containing the dispersion; the solid dispersion of the present invention, which contains a poorly soluble component with improved dissolvability, can be ...


7
Shinji Fujimoto, Toshinobu Uemura, Kantaro Kaneko, Yoshinobu Fukumori: Dry Coating using Twin-Screw Kneader. Kurimoto, Kratz Quintos & Hanson, December 10, 2009: US20090304800-A1

An object of the present invention is to provide a dry coating process that can produce a dry-coated preparation in a large amount. A large amount of dry-coated preparation can be produced more efficiently, than by prior-art processes, by a process in which a material containing core particles and a ...