1
Todd K Whitehurst, James P McGivern, Rafael Carbunaru, Matthew I Haller, Tom Xiaohai He, Kerry Bradley: Vagus nerve stimulation via unidirectional propagation of action potentials. Advanced Bionics Corporation, Fish & Richardson P C, November 6, 2007: US07292890 (276 worldwide citation)

Methods of stimulating a vagus nerve include providing at least one implantable stimulator with at least two electrodes, configuring the electrodes to apply stimulation that unidirectionally propagates action potentials along a vagus nerve, and applying the stimulation to the vagus nerve to effectiv ...


2
Tom Xiaohai He, James P McGivern, Todd K Whitehurst: Surgical insertion tool. Advanced Bionics Corporation, Laura Haburay Bishop, Bryant R Gold, June 24, 2003: US06582441 (273 worldwide citation)

A tool is provided for facilitating determining a proper location for an implantable device or medication, and for then delivering the implant to the precise location determined with the tool. To determine the target location, the tool may include a component for testing target locations, such as a ...


3
Tom Xiaohai He, Matthew Isaac Haller: Implantable stimulator with integrated plastic housing/metal contacts and manufacture and use. Boston Scientific Neuromodulation Corporation, Frommer Lawrence & Haug, Bruce E Black, July 20, 2010: US07761165 (176 worldwide citation)

An implantable stimulator system includes a plastic housing, an electronic subassembly and at least one metal contact. The plastic housing defines an interior chamber and an exterior. The electronic subassembly is disposed in the interior chamber of the plastic housing. The at least one metal contac ...


4
Todd K Whitehurst, Rafael Carbunaru, James P McGivern, Matthew I Haller, Tom Xiaohai He, Kerry Bradley, Janusz A Kuzma: Implantable microstimulators and methods for unidirectional propagation of action potentials. Boston Scientific Neuromodulation Corporation, Frommer Lawrence & Haug, Bruce E Black, December 28, 2010: US07860570 (164 worldwide citation)

Miniature implantable stimulators (i.e., microstimulators) are capable of producing unidirectionally propagating action potentials (UPAPs). The methods and configurations described may, for instance, arrest action potentials traveling in one direction, arrest action potentials of small diameters ner ...


5
Todd K Whitehurst, James P McGivern, Rafael Carbunaru, Matthew I Haller, Tom Xiaohai He, Kerry Bradley: Cavernous nerve stimulation via unidirectional propagation of action potentials. Advanced Bionics Corporation, Fish & Richardson P C, April 10, 2007: US07203548 (138 worldwide citation)

Methods of using unidirectionally propagating action potentials (UPAPs) for cavernous nerve stimulation and for certain disorders are provided. Stimulators capable of creating such UPAPs include, but are not limited to, miniature implantable stimulators (i.e., microstimulators), possibly with progra ...


6
Tom Xiaohai He: Stimulator system with electrode array and the method of making the same. Boston Scientific Neuromodulation Corporation, Frommer Lawrence & Haug, Patrick R Turner, May 8, 2012: US08175710 (112 worldwide citation)

An implantable microstimulator can include a housing with a surface containing a metal region. The housing defines an exterior and an interior. At least one conductive electrode is disposed on the exterior of the housing over the metal region of the housing. Adhesive is disposed between the metal re ...


7
Anne M Pianca, Carla M Mann, Tom Xiaohai He, Michael Dogali: Cranial sealing plug. Advanced Bionics Corporation, Victoria A Poissant, Bryant R Gold, February 28, 2006: US07004948 (53 worldwide citation)

Various embodiments of a burr hole plug assembly offer significant improvements for allowing lead and/or cannula access through a burr hole drilled through a patient's skull in connection with a Deep Brain Stimulation system, and subsequent sealing of such burr hole. The various burr hole plug assem ...


8
Janusz A Kuzma, Lani A Smith, Chuladdatta Tehnuwara, Tom Xiaohai He: Implantable electrode, insertion tool for use therewith, and insertion method. Boston Scientific Neuromodulation Corporation, Darby & Darby P C, Bruce E Black, December 2, 2008: US07460913 (38 worldwide citation)

An electrode system includes an implantable electrode having at least one electrode contact, an insertion tool, and a technique or method that allows the electrode contact to be positioned within soft tissue at a selected target stimulation site.


9
Tom Xiaohai He, Michael S Colvin: Hermetically bonding ceramic and titanium with a Ti-Pd braze interface. Boston Scientific Neuromodulation Corporation, Frommer Lawrence & Haug, Bruce E Black, August 10, 2010: US07771838 (35 worldwide citation)

A component assembly for use in living tissue comprises: a ceramic part; a metal part; and a titanium palladium (Ti—Pd) interface layer for bonding said ceramic part to the metal part. In one embodiment, the interface layer may be formed from a single titanium layer in contact with a single palladiu ...


10
Janusz A Kuzma, Tom Xiaohai He, Anne Pianca: Implantable microstimulator with dissecting tip and/or retrieving anchor and methods of manufacture and use. Boston Scientific Neuromodulation Corporation, Fish & Richardson P C, October 28, 2008: US07444180 (32 worldwide citation)

An implantable microstimulator can include a housing having a first end; an electronic subassembly disposed within the housing; a plurality of electrodes disposed on the housing and coupled to the electronic subassembly; and a dissecting tip disposed at the first end of the housing. Another implanta ...



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