1
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Philip K Ahring: 1,4-diazabicycloalkane derivatives, their preparation and use. NeuroSearch, Birch Stewart Kolasch & Birch, May 22, 2007: US07220741 (6 worldwide citation)

This invention relates to novel 1,4-diazabicycloalkane derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. ...


2
Bo Skaaning Jensen, Tino Dyhring Jørgensen, Philip K Ahring, Palle Christophersen, Dorte Strøbaek, Lene Teuber, Søren Peter Olesen: Use of isatin derivatives as ion channel activating agents. Neurosearch, Birch Stewart Kolasch & Birch, November 29, 2005: US06969729 (5 worldwide citation)

The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channe ...


3
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Daniel B Timmermann: Diazabicyclic aryl derivatives as cholinergic receptor modulators. NeuroSearch, Birch Stewart Kolasch & Birch, February 16, 2010: US07662808 (3 worldwide citation)

This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the trea ...


4
Dan Peters, Daniel B Timmermann, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen: Azabicyclic aryl derivatives and their medical use. Neurosearch, Birch Stewart Kolasch & Birch, January 26, 2010: US07652010 (3 worldwide citation)

Azabicyclo pyridazinyl compounds including azabicyclooctyl-pyridazinyl-oxy compounds, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile, the compounds may be used for the ...


5
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Daniel B Timmermann: Azabicyclic aryl derivatives. NeuroSearch, Birch Stewart Kolasch & Birch, April 7, 2009: US07514450 (2 worldwide citation)

This invention relates to novel azabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to ...


6
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Daniel B Timmermann: Dimeric azacyclic compounds and their use. Neurosearch, Birch Stewart Kolasch & Birch, March 9, 2010: US07674899 (2 worldwide citation)

This invention relates to novel azacyclic derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CN ...


7
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Philip K Ahring, Tino Dyhring Jørgensen, Michael R Schrimpf, Kevin B Sippy: Quinuclidine derivatives and their pharmaceutical use. Neurosearch, Abbott Laboratories, Birch Stewart Kolasch & Birch, July 6, 2010: US07750022

This invention relates to novel quinuclidine derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system ...


8
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Daniel B Timmermann: Diazabicyclic aryl derivatives as cholinergic receptor modulators. Neurosearch, Birch Stewart Kolasch & Birch, August 7, 2012: US08236793

This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the trea ...


9
Dan Peters, Gunnar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Philip K Ahring: Diazabicyclic aryl derivatives. Neurosearch, Birch Stewart Kolasch & Birch, March 16, 2010: US07678788

This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related ...


10
Dan Peters, Gurmar M Olsen, Elsebet Østergaard Nielsen, Tino Dyhring Jørgensen, Philip K Ahring: Azacyclic ethynyl derivatives. Neurosearch, Birch Stewart Kolasch & Birch, February 23, 2010: US07667040

Azacyclic ethynyl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders a ...