1
Stéphane De Lombaert
Rajagopal Bakthavatchalam, Timothy M Caldwell, Bertrand L Chenard, Stéphane De Lombaert, Kevin J Hodgetts: Substituted quinolin-4-ylamine analogues. Neurogen Corporation, Edwards Angell Palmer & Dodge, Peter F Corless, Mark D Russett, February 10, 2009: US07488740 (6 worldwide citation)

Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion ...


2
Stéphane De Lombaert
Rajagopal Bakthavatchalam, Charles A Blum, Harry Brielmann, Timothy M Caldwell, Stéphane De Lombaert, Kevin J Hodgetts, Xiaozhang Zheng, Taeyoung Yoon: Substituted quinazolin-4-ylamine analogues. Neurogen Corporation, Edwards Angell Palmer & Dodge, Peter F Corless, Mark D Russett, December 4, 2007: US07304059 (3 worldwide citation)

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated compani ...


3
Stéphane De Lombaert
Rajagopal Bakthavatchalam, Timothy M Caldwell, Bertrand L Chenard, Stéphane De Lombaert, Kevin J Hodgetts: Substituted quinolin-4-ylamine analogues. Neurogen Corporation, Edward Angell Palmer & Dodge, November 19, 2009: US20090286767-A1

Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion ...


4
Rajagopal Bakthavatchalam, Charles A Blum, Harry Brielmann, Timothy M Caldwell, Stephane De Lombaert, Kevin J Hodgetts, Xiaozhang Zheng: Substituted quinazolin-4-ylamine analogues. Neurogen Corporation, Peter F Corless, John B Alexander, Edwards Angell Palmer & Dodge, July 11, 2006: US07074799 (23 worldwide citation)

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated compani ...


5
Rajagopal Bakthavatchalam, Charles A Blum, Harry Brielmann, Timothy M Caldwell, Stéphane DeLombaert, Kevin J Hodgetts, Xiaozhang Zheng: Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators. Neurogen Corporation, Edwards Angell Palmer & Dodge, Peter F Corless, Mark D Russett, October 7, 2008: US07432275 (8 worldwide citation)

Acid-substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated co ...


6
Alan Hutchison, Linda M Gustavson, John M Peterson, Dario Doller, Timothy M Caldwell, Taeyoung Yoon, Wallace C Pringle, Yiping Shen, Cheryl Steenstra: Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues. Neurogen Corporation, Ann Kadlecek, Seth Fidel, October 11, 2005: US06953801 (5 worldwide citation)

Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are partic ...


7
Rajagopal Bakthavatchalam, Timothy M Caldwell, Bertrand L Chenard, Kevin J Hodgetts, Scott Michael Capitosti: Substituted biaryl quinolin-4-ylamine analogues. Neurogen Corporation, Edwards Angell Palmer & Dodge, Peter F Corless, Mark D Russett, May 3, 2011: US07935702 (3 worldwide citation)

Substituted biaryl quinolin-4-ylamine analogues of Formula I are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, do ...


8
Linghong Xie, Joseph W Ochterski, Yang Gao, Bingsong Han, Timothy M Caldwell, Yuelian Xu, John M Peterson, Ping Ge, Robert Ohliger: Dipiperazinyl ketones and related analogues. Neurogen Corporation, Cantor Colburn, December 14, 2010: US07851474 (1 worldwide citation)

Dipiperazinyl ketones and related analogues are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, dom ...


9
Alan J Hutchison, Linda M Gustavson, John M Peterson, Dario Doller, Timothy M Caldwell, Taeyoung Yoon, Wallace C Pringle, Rajagopal Bakthavatchalam, Yiping Shen, Cheryl K Steenstra, Helen Yin, Robert W DeSimone, Xiao shu He: Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues. Neurogen Corporation, Ann T Kadlecek, Seth A Fidel, July 10, 2007: US07241765

Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are partic ...


10
Rajagopal Bakthavatchalam, Charles A Blum, Harry Brielmann, Timothy M Caldwell, Stephane De Lombaert, Kevin J Hodgetts, Taeyoung Yoon, Xiaozhang Zheng: Substituted quinazolin-4-ylamine analogues. McDonnell Boehnen Hulbert & Berghoff, June 3, 2004: US20040106616-A1

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated compani ...