1
Thompson John E: Psuedorandom quantizing systems for transmitting television signals. The Post Office, February 9, 1971: US3562420 (60 worldwide citation)

A pseudo-random quantizing system for television signals comprises a PCM transmission channel which includes a multilevel quantizer, and also includes means for generating a multilevel dither signal produced from pseudo-random binary noise signals and arranged to give a nonwhite predominantly high f ...


2
Thompson John E, Taylor Catherine: Inhibition of apoptosis-specific elf-5a (“eif-5a1”) with antisense oligonucleotides and sirnas as anti-inflammatory therapeutics. Senesco Technologies, Thompson John E, Taylor Catherine, LAVENUE Teresa A, January 27, 2005: WO/2005/007853 (11 worldwide citation)

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5A1, nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of ...


3
Thompson John E, Taylor Catherine, Cliché Dominic, Heikkila Elisabeth Margaret, Senchyna Diane Michelle, Flanagan John Gerard: Use of antisense oligonucleotides or sirna to suppress expression of eif-5a1. Senesco Technologies, Thompson John E, Taylor Catherine, Cliché Dominic, Heikkila Elisabeth Margaret, Senchyna Diane Michelle, Flanagan John Gerard, LAVENUE Teressa A, September 16, 2004: WO/2004/078940 (9 worldwide citation)

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRN ...


4
Thompson John E: Isoforms of elf-5a: senescence-induced elf5a; wounding-induced elf-5a; growth elf-5a; and dhs. Senesco Technologies, Thompson John E, LAVENUE Teresa A, December 29, 2004: WO/2004/113528 (5 worldwide citation)

The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ('eIF-5A'): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the ex ...


5
Thompson John E, Taylor Catherine, Cliche Dominic, Dinarello Charles, Reznikov Leonid, Pomerantz Benjamin: Nucleic acids, polypeptides, and methods for modulating apoptosis. Senesco Technologies, WOMBLE CARLYLE SANDRIDGE PO Box 7037 Atlanta GA 30357 0037, May 6, 2004: WO/2004/037984 (2 worldwide citation)

The present invention provides methods of identifying an incidence of ischemia in mammalian tissue, particularly mammalian heart tissue. Further, a method of reducing apoptosis in mammalian tissue, preferably heart tissue, is provided. These methods involve measuring and comparing the gene expressio ...


6
Thompson John E: Use of eif-5a1 sirna and antisense to treat sepsis or haemorrhagic shock. Senesco, Technologies, LAVENUE Teresa A, September 27, 2007: WO/2007/109674 (1 worldwide citation)

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5-A1, nucleic acids and polypeptides and methods for down regulating pro-inflammatory cytokines in a mammal by administering siRNA against eIF-5A1 to the mamma ...


7
Thompson John E, Wang Tzann Wei, Lu Dongen Lily: Dna encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5a, transgenic plants and a method for controlling senescence programmed and cell death in plants. Senesco, zhang anyu, April 20, 2005: CN01822314 (1 worldwide citation)

Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescen ...


8
Taylor Catherine, Wang Tzann Wei, Petrov Larry, Carlson John C, Narayansingh Richard, Thompson John E, Cliche Dominic, Hopkins Marianne: Nucleic acids, polypeptides, and methods for modulating apoptosis. Senesco, June 29, 2005: EP1546375-A2

The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, an ...


9
Thompson John E, Lu Dongen Lily, Wang Tzann Wei: Dna encoding a plant deoxyhypusine synthase, a plant eukaryotic initation factor 5a, transgenic plants and a method for controlling senescene and programmed cell death in plants. Senesco, January 23, 2008: EP1881072-A1

Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescen ...


10
Thompson John E, Mcnamara Linda: Isoforms of elf-5a and methods of using same. Senesco Technologies, January 28, 2009: EP2019142-A2

The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods invo ...