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Kania Robert Steven, Bender Steven Lee, Borchardt Allen J, Braganza John F, Cripps Stephan James, Hua Ye, Johnson Michael David, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Tempczyk Russell Anna Maria, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan, Collins Michael Raymond: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharmaceuticals, PINO Mark J, January 11, 2001: WO/2001/002369 (3 worldwide citation)

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...


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Teng Min, Truesdale Larry Kenneth, Bhumralkar Dilip, Kiel Dan, Johnson Michael D, Thomas Christine, Jorgensen Anker Steen, Madsen Peter, Olesen Preben Houlberg, Knudsen Liselotte Bjerre, Petterson Ingrid Vivika, Cornelis de Jong Johannes, Behrens Carsten, Kodra Janos Tibor, Lau Jesper: Non-peptide glp-1 agonists. Novo Nordisk, Agouron Pharma, October 24, 2001: EP1147094-A1 (2 worldwide citation)

Novel non-peptide GLP-1 agonists, pharmaceutical compositions comprising them, use of the non-peptide GLP-1 agonists for the preparation of pharmaceutical compositions and methods for the treatment and/or prevention of disorders and diseases wherein an activation of the human GLP-1 receptor is benef ...


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Collins Michael Raymond, Tempczyk Russell Anna Maria, Hua Ye, Johnson Michael David, Bender Steven Lee, Kania Robert Steven, Borchardt Allen J, Braganza John F, Cripps Stephan James, Johnson Theodore Otto Jr, Luu Hiep The, Palmer Cynthia Louise, Reich Siegfried Heinz, Teng Min, Thomas Christine, Varney Michael David, Wallace Michael Brennan: Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use. Agouron Pharma, January 11, 2006: EP1614683-A1 (1 worldwide citation)

Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The inv ...


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Alessi Dario, Van Aalten Daan, Thomas Christine: Methods for identifying substances interacting with pleckstrin homologydomains, and proteins containing mutated pleckstrin homology domains. Univ Dundee, April 7, 2004: GB2393725-A

A method for selecting or designing a compound for modulating the activity of Tandem PH domain containing Protein (TAPP), the method comprising the step of using molecular modelling means to select or design a compound that is predicted to interact with the phosphoinositide binding domain of TAPP, w ...