1
Manoj C Desai, Terry J Rosen: 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use. Pfizer, Peter C Richardson, Paul H Ginsburg, Karen DeBenedictis, August 3, 1993: US05232929 (36 worldwide citation)

The present invention relates to novel 3-aminopiperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, Y and m are as defined below. These nove ...


2
Bruce E Firth, Terry J Rosen: Preparation of ortho-alkylated phenols. UOP, James R Hoatson Jr, Eugene I Snyder, William H Page II, May 8, 1984: US04447657 (36 worldwide citation)

Alkyl phenyl ethers may be induced to undergo thermal rearrangement on an alumina catalyst to afford the isomeric ortho-alkylphenol. Such rearrangement generally occurs under milder conditions than does the alkylation of a phenol with an olefin using the same alumina as an alkylating catalyst. Yield ...


3
Bruce E Firth, Terry J Rosen: Preparation of 2-t-butyl-4-alkoxy- and 4-hydroxyphenols. UOP, James R Hoatson Jr, Eugene I Snyder, William H Page II, August 14, 1984: US04465871 (32 worldwide citation)

Tertiary alkyl phenyl ethers may be induced to undergo thermal rearrangement on an alumina catalyst to afford the isomeric ortho-t-alkylphenol. Such rearrangement generally occurs under milder conditions than does the alkylation of a phenol with an olefin using the same alumina as an alkylating cata ...


4
Terry J Rosen: Azabicyclo amides and esters as 5-HT3 receptor antagonists. Pfizer, Peter C Richardson, Gregg C Benson, August 29, 1995: US05446050 (20 worldwide citation)

Novel azabicyclo amides and esters as antagonists at the 5-HT.sub.3 receptor and useful as anti-emetic agents.


5
Daniel W Norbeck, Terry J Rosen, Hing L Sham: Carbocyclic nucleoside analogs with antiviral activity. Abbott Laboratories, Steven R Crowley, January 29, 1991: US04988703 (20 worldwide citation)

An antiviral compound of the formula: ##STR1## wherein A is selected from a purin-9-yl group, a heterocyclic isostere of a purin-9-yl group, a pyrimidin-1-yl group and a heterocyclic isostere of a pyrimidin-1-yl group; and


6
Manoj C Desai, Terry J Rosen: 3-aminopiperidine derivatives and related nitrogen containing heterocycles. Pfizer, Peter C Richardson, Paul H Ginsburg, Karen DeBenedictis, July 26, 1994: US05332817 (17 worldwide citation)

The present invention relates to novel 3-amino-piperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, Y and m are as defined below. These nov ...


7
Daniel T Chu, Terry J Rosen, Curt S Cooper: 7-cycloalkyl naphthyridines. Abbott Laboratories, Steven F Weinstock, Edward H Gorman Jr, November 14, 1989: US04880814 (16 worldwide citation)

The present invention includes compounds represented by the formula: ##STR1## wherein R.sub.1 is a hydroxy, a C.sub.1 to C.sub.6 alkoxy, benzoxy, or an alkylcarbonyloxymethoxy group, or R.sub.3 together with R.sub.1 forms a group of the formula --Y--NH-- where Y is oxygen or sulfur; or R.sub.3 is hy ...


8
Terry J Rosen, Dennis M Godek, Sally Gut, Lewin Wint: Preparation of substituted piperidines. Pfizer, Peter C Richardson, Paul H Ginsburg, Garth Butterfield, November 15, 1994: US05364943 (11 worldwide citation)

Substituted piperidines and related compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are herein defined are disclosed.


9
Arthur A Nagel, James P Rizzi, Terry J Rosen: Arylthiazolylimidazoles. Pfizer, Peter C Richardson, J Trevor Lumb, James M McManus, April 3, 1990: US04914207 (10 worldwide citation)

Arylthiazolylimidazoles as 5HT.sub.3 antagonists useful in the treatment of nausea, anxiety, pain, schizoprenia and gastrointestinal disorders.


10
Julio Cesar Medina, David Louis Clark, John A Flygare, Terry J Rosen, Bei Shan: Substituted benzene compounds as antiproliferative and cholesterol lowering action. Tularik, Townsend and Townsend and Crew, September 4, 2001: US06284923 (9 worldwide citation)

The invention provides compounds, compositions and methods relating to novel electrophilic aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, psoriasis, vascula ...