1
Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A Munoz, Jason Speake, Daniel Yohannes: Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]OCT-3-yl)-3,5-difluorobenzamide. Targacept, Amy H Fix, July 2, 2013: US08476296 (2 worldwide citation)

The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety ...


2
Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A Munoz, Jason Speake, Daniel Yohannes: Preparation and therapeutic applications of (2S, 3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]OCT-3-yl)-3,5-difluorobenzamide. Targacept, Amy H Fix, Womble Carlyle Sandridge & Rice, December 2, 2014: US08901151 (1 worldwide citation)

The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety ...


3
Merouane Bencherif, Nikolai Federov, Terry Hauser, Kristen G Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A Munoz, Jason Speake, Daniel Yohannes: Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide. BRINKS GILSON & LIONE, November 3, 2015: US09173876

The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety ...


4
Merouane Bencherif, Kristen Jordan, Terry Hauser, Steven M Toler, Sharon Rae Letchworth, David C Kombo: Treatment with alpha7 selective ligands. Targacept, October 27, 2011: US20110262407-A1

The present invention includes methods, uses, and selective alpha7 nAChR ligands for treating or preventing disease and disorders in which stimulation of neurogenesis is ameliorative; namely, wherein the recruitment of neurogenesis is therapeutic.


5
Merouane Bencherif, Gregory J Gatto, Terry Hauser, Kristen G Jordan, Sharon R Letchworth: Alpha 7 nicotinic agonists and antipsychotics. Targacept, March 10, 2011: US20110059947-A1

The present invention relates to a synergistic combination of an alpha7 (α7) nicotinic agonist and an antipsychotic agent.


6
Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A Munoz, Jason Speake, Daniel Yohannes: Preparation and therapeutic applications of (2s,3r)-n-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide. Targacept, October 20, 2011: US20110257224-A1

The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetyl-choline receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety ...