1
Bouma Brett Eugene, Tearney Guillermo J, Yelin Dvir, Yun Seok Hyun: Spectral encoding heterodyne interferometry techniques for imaging. The General Hospital Corporation, Bouma Brett Eugene, Tearney Guillermo J, Yelin Dvir, Yun Seok Hyun, ABELEV Gary, December 7, 2006: WO/2006/130797 (119 worldwide citation)

Systems, arrangements and methods for obtaining three-dimensional imaging data are provided. For example, a broadband light source (100) can provide a particular radiation. A first electro-magnetic radiation can be focused and diffracted, and then provided to at least one sample (140) to generate a ...


2
Yun Seok Hyun Ph D, Bouma Brett Eugene Ph D, Tearney Guillermo J Md Ph D, Boer Johannes Fitzgerald de Ph D: Method and apparatus for performing optical imaging using frequency-domain interferometry. The General Hospital Corporation, Yun Seok Hyun Ph D, Bouma Brett Eugene Ph D, Tearney Guillermo J Md Ph D, Boer Johannes Fitzgerald de Ph D, ABELEV Gary, May 26, 2005: WO/2005/047813 (85 worldwide citation)

An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An inte ...


3
Tearney Guillermo J, Shishkov Milen, Bouma Brett E: Method and apparatus for imaging of vessel segments. The General Hospital Corporation, Tearney Guillermo J, Shishkov Milen, Bouma Brett E, ABELEV Gary, March 2, 2006: WO/2006/024015 (35 worldwide citation)

An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (208) (e.g., a housing), a fluid delivery arrangement and an imaging arrangement (204). The housing includes an ape ...


4
Yun Seok Hyun, Bouma Brett Eugene, Tearney Guillermo J, Deboer Johannes F: System and method for optical coherence imaging. The General Hospital Corporation, Yun Seok Hyun, Bouma Brett Eugene, Tearney Guillermo J, Deboer Johannes F, ABELEV Gary, April 13, 2006: WO/2006/039091 (32 worldwide citation)

A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signa ...


5
Vakoc Benjamin J, Yun Seok Hyun, Tearney Guillermo J, Bouma Brett Eugene, de, Boer Johannes F: Apparatus, method and system for performing phase-resolved optical frequency domain imaging. The General Hospital Corporation, Vakoc Benjamin J, Yun Seok Hyun, Tearney Guillermo J, Bouma Brett Eugene, de, Boer Johannes F, ABELEV Gary, December 7, 2006: WO/2006/130802 (30 worldwide citation)

Apparatus, system and method are provided which utilize signals received from a reference and a sample. In particular, a radiation is provided which includes at least one first electro-magnetic radiation directed to the sample and at least one second electro-magnetic radiation directed to the refere ...


6
Shishkov Milen, Bouma Brett Eugene, Tearney Guillermo J: System and method for optical coherence imaging. The General Hospital Corporation, Shishkov Milen, Bouma Brett Eugene, Tearney Guillermo J, ABELEV Gary, April 6, 2006: WO/2006/037132 (20 worldwide citation)

Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical coopera ...


7
Tearney Guillermo J, Shishkov Milen, Bouma Brett E, Vakoc Benjamin J, Nishioka Norman S: Methods and systems for optical imaging of epithelial luminal organs by beam scanning thereof. The General Hospital Corporation, Tearney Guillermo J, Shishkov Milen, Bouma Brett E, Vakoc Benjamin J, Nishioka Norman S, ABELEV Gary, July 26, 2007: WO/2007/084995 (20 worldwide citation)

Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can ...


8
Yelin Dvir, Bouma Brett E, Tearney Guillermo J, Iftimia Nicusor: Method and apparatus for three-dimensional spectrally encoded imaging. The General Hospital Corporation, Yelin Dvir, Bouma Brett E, Tearney Guillermo J, Iftimia Nicusor, ABELEV Gary, June 16, 2005: WO/2005/054780 (5 worldwide citation)

A method and apparatus for obtaining three-dimensional surface measurements using phase-sensitive spectrally encoded imaging is described. Both transverse and depth information is transmitted through a single-mode optical fiber, allowing this technique to be incorporated into a miniature probe.


9
Tearney Guillermo J, Iftimia Nicusor, Bouma Brett E: Speckle reduction in optical coherence tomography by path length encoded angular compounding. The General Hospital Corporation, Tearney Guillermo J, Iftimia Nicusor, Bouma Brett E, ABELEV Gary, October 14, 2004: WO/2004/088361 (4 worldwide citation)

Speckle, a factor reducing image quality in optical coherence tomography ('OCT'), can limit the ability to identify cellular structures that are important for the diagnosis of a variety of diseases. The present invention allows for an implementation of an angular compounding, angular compounding by ...


10
Nadkarni Seemantini K, Tearney Guillermo J, Bouma Brett E, Vakoc Benjamin J, Anderson Richard Rox: System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages. The General Hospital Corporation, Nadkarni Seemantini K, Tearney Guillermo J, Bouma Brett E, Vakoc Benjamin J, Anderson Richard Rox, ABELEV Gary, September 13, 2007: WO/2007/103721 (4 worldwide citation)

An apparatus and method according to the present invention can be provided, e.g., for a cell specific laser therapy of atherosclerotic plaques, particularly to systems and methods for targeting endogenous light absorbers present within plaque macrophages and exogenous nanoparticle targeting. In one ...