1
John D Madden, Tanya S Kanigan, Serge Lafontaine, Ian W Hunter: Conducting polymer actuator. Massachusetts Institute of Technology, Bromberg & Sunstein, June 19, 2001: US06249076 (427 worldwide citation)

Embodiments of actuators having an active member including a polymer having a surface, an electrolyte coupled to the surface, and an electrolyte are provided. Actuators which, when an electrical potential is applied across the electrolyte between the active member and the counter electrode, exert fo ...


2
Robert A Hess, John Linton, Tanya S Kanigan, Colin Brenan, Can Ozbal: Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof. BioTrove, Fish & Richardson P C, April 6, 2004: US06716629 (125 worldwide citation)

The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological com ...


3
John Linton, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya S Kanigan, Kristine Friesen, Arrin Katz, Colin Brenan, Tom Morrison, Javier Garcia: Assay apparatus and method using microfluidic arrays. BioTrove, March 23, 2010: US07682565 (35 worldwide citation)

A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers t ...


4
Ian Hunter, Colin J H Brenan, Tanya S Kanigan: Methods for screening substances in a microwell array. Massachusetts Institute of Technology, Bromberg & Sunstein, May 17, 2005: US06893877 (32 worldwide citation)

Methods for manufacturing and using an apparatus for manipulating and analyzing a large number of microscopic samples of a liquid or materials, including cells, in liquid suspension. Parallel through-holes are formed in a platen and loaded with a liquid. Loading may be performed in such a way as to ...


5
Ian Hunter, Colin J H Brenan, Tanya S Kanigan: Methods for filing a sample array by droplet dragging. Massachusetts Institute of Technology, Edwards Angell Palmer & Dodge, Brian R Landry, Christine C O Day, June 16, 2009: US07547556 (17 worldwide citation)

A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a hydrophilic surface, and the receptacles are separated by a hydrophobic surface. The system has a liquid transfer ...


6
Tanya S Kanigan, Steve Smith, John Linton, Robert Hess, Karl Yoder, Colin Brennan: Nanoliter array loading. Life Technologies Corporation, January 31, 2012: US08105554 (7 worldwide citation)

An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so tha ...


7
Ian Hunter, Colin J H Brenan, Tanya S Kanigan: Systems for filling a sample array by droplet dragging. Massachusetts Institute of Technology, Steptoe & Johnson, October 4, 2011: US08029745 (4 worldwide citation)

Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface, th ...


8
Robert A Hess, John Linton, Tanya S Kanigan, Colin Brenan, Can Ozbal: Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof. John W Freeman Esq, Fish & Richardson PC, July 18, 2002: US20020094533-A1 (2 worldwide citation)

The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological com ...


9
Robert A Hess, John Linton, Tanya S Kanigan, Colin Brenan, Can Ozbal: Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof. Biotrove a Delaware Corporation, John W Freeman Esq, Fish & Richardson PC, September 25, 2003: US20030180807-A1 (1 worldwide citation)

The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological com ...


10
Robert A Hess, John Linton, Tanya S Kanigan, Colin Brenan, Can Ozbal: Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof. Biotrove a Delaware corporation, John W Freeman Esq, Fish & Richardson PC, July 3, 2003: US20030124716-A1 (1 worldwide citation)

The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological com ...