1
Tammy Burd Mehta, Anne R Kopf Sill, J Wallace Parce, Andrea W Chow, Luc J Bousse, Michael R Knapp, Theo T Nikiforov, Steve Gallagher: Manipulation of microparticles in microfluidic systems. Caliper Technologies, Matthew B Murphy, Donald R McKenna, Quine Intellectual Property Law Group P C, October 14, 2003: US06632655 (371 worldwide citation)

Arrays of flowable or fixed particle sets are used in microfluidic systems for performing assays and modifying hydrodynamic flow. Also provided are assays utilizing flowable or fixed particle sets within a microfluidic system, as well as kits, apparatus and integrated systems comprising arrays and a ...


2
J Wallace Parce, Theo T Nikiforov, Tammy Burd Mehta, Anne R Kopf Sill, Andrea W Chow, Michael R Knapp: Sequencing by incorporation. Caliper Technologies, Stacy Landry, Gary Baker, Quine Intellectual Property Law Group P C, September 2, 2003: US06613513 (192 worldwide citation)

Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carb ...


3
J Wallace Parce, Theo T Nikiforov, Tammy Burd Mehta, Anne R Kopf Sill, Andrea W Chow, Michael R Knapp: Sequencing by incorporation. Caliper Life Sciences, Donald R McKenna, Ann C Petersen, September 12, 2006: US07105300 (159 worldwide citation)

Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carb ...


4
Tammy Burd Mehta, Anne R Kopf Sill: Microfluidic matrix localization apparatus and methods. Caliper Technologies, Gulshan H Shaver, The Law Offices of Jonathan Alan Quine, October 23, 2001: US06306590 (116 worldwide citation)

Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided.


5
Andrea W Chow, Robert S Dubrow, J Wallace Parce, Steven A Sundberg, Jeffrey A Wolk, Ring Ling Chien, Steven James Gallagher, Michael R Knapp, Anne R Kopf Sill, Tammy Burd Mehta: External material accession systems and methods. Caliper Technologies, Jonathan Alan Quine, Stacy Landry, Quine Intellectual Property Law Group P C, September 10, 2002: US06447661 (75 worldwide citation)

Methods, apparatus and systems are provided for introducing large numbers of different materials into a microfluidic analytical device rapidly, efficiently and reproducibly. In particular, improved integrated pipettor chip configurations, e.g. sippers or electropipettors, are described which are cap ...


6
Tammy Burd Mehta: Methods and systems for performing multiple reactions by interfacial mixing. Caliper Life Sciences, Donald R McKenna, Ann C Petersen, December 20, 2005: US06977163 (46 worldwide citation)

Methods and systems of performing multiple reactions in a high throughput format by utilizing interfacial mixing of adjacently positioned reagent slugs in a fluid conduit. Preferred applications of the methods and systems are in performing biochemical analyses, including genotyping experiments for m ...


7
Tammy Burd Mehta: PCR compatible nucleic acid sieving matrix. Caliper Lifesciences, Cardinal Law Group, April 21, 2009: US07521186 (44 worldwide citation)

Sieving mediums comprising less than about 0.5% polymer, less than about 0.4% polymer, and 0.35% polymer or less are used to perform nucleic acid separations and PCR. The low polymer concentration does not inhibit PCR reactions and is sufficient for performing nucleic acids separations. Microfluidic ...


8
Tammy Burd Mehta, Anne R Kopf Sill: Microfluidic matrix localization apparatus and methods. Caliper Life Sciences, Donald R McKenna, Ann C Petersen, January 2, 2007: US07156969 (13 worldwide citation)

Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided.


9
J Wallace Parce, Theo T Nikiforov, Tammy Burd Mehta, Anne R Kopf Sill, Andrea W Chow, Michael R Knapp: Sequencing by incorporation. Caliper Lifesciences, Cardinal Law Group, July 28, 2009: US07566538 (8 worldwide citation)

Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carb ...


10
J Wallace Parce, Theo T Nikiforov, Tammy Burd Mehta, Anne R Kopf Sill, Andrea W Chow, Michael R Knapp: Sequencing by incorporation. Caliper Life Sciences, Ann C Peterson, Donald R McKenna, March 18, 2008: US07344865 (4 worldwide citation)

Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carb ...