1
Carter B Green, Tetsuo Nakatsu, Takero Ishizaki, Andrew T Lupo Jr: (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate. Takasago International Corporation, Takasago International Corporation, Darby & Darby, October 18, 2005: US06956139 (13 worldwide citation)

A cooling sensate compound having the general formula (I): where n is an integer from 2 to 6. The compound is effective in imparting a refreshing and cooling sensation of long duration. A cooling sensate composition having the general formula (I) is used in a variety of formulations to impart the re ...


2
Tohru Yokozawa, Noboru Sayo, Takao Saito, Takero Ishizaki: Optically active diphosphine compound, production intermediate thereof, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex. Takasago International Corporation, Sughrue Mion Zinn Macpeak & Seas PLLC, December 25, 2001: US06333291 (8 worldwide citation)

This invention provides a novel diphosphine compound which is useful as a ligand of catalysts for asymmetric synthesis reactions, particularly asymmetric hydrogenation reaction. Particularly, it provides a diphosphine compound represented by a general formula (1):


3
Tetsuro Yamasaki, Hidenori Kumobayashi, Noboru Sayo, Toshiyuki Murayama, Noboru Sano, Takero Ishizaki: Process for producing optically active diaminohexanone derivative. Takasago International Corporation, Oblon Spivak McClelland Maier & Neustadt, June 4, 1996: US05523458 (2 worldwide citation)

Disclosed herein is a process for producing a (2S,5S)-2,5-diamino-1,6-diphenyl-3-hexanone derivative represented by the formula (1): ##STR1## wherein R.sup.1 means a lower alkylcarbonyl group, a halogen-substituted lower alkylcarbonyl group, an arylcarbonyl group or a lower alkoxycarbonyl group, and ...


4
Tohru Yokozawa, Takao Saito, Noboru Sayo, Takero Ishizaki: Production process of diphosphine oxide and diphosphonate. Takasago International Corporation, Sughrue Mion PLLC, October 29, 2002: US06472539

A process for producing a diphosphine oxide or diphosphonate represented by formula (1) as defined, which comprises treating, with a base, a phosphine compound represented by formula (2) as defined and adding the thus-treated phosphine compound to a nonpolar solvent having an oxidative metal compoun ...


5
Tetsuro Yamasaki, Hidenori Kumobayashi, Noboru Sayo, Toshiyuki Murayama, Noboru Sano, Takero Ishizaki: Process for producing optically active diaminohexanone derivative. Takasago International Corporation, Oblon Spivak McClelland Maier & Neustadt P C, May 20, 1997: US05631397

Disclosed herein is a process for producing a (2S,5S)-2,5-diamino-1,6-diphenyl-3-hexanone derivative represented by the formula (1): ##STR1## wherein R.sup.1 means a lower alkylcarbonyl group, a halogen-substituted lower alkylcarbonyl group, an arylcarbonyl group or a lower alkoxycarbonyl group, and ...


6
Carter B Green, Tetsuo Nakatsu, Takero Ishizaki, Andrew T Lupo: (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate. Darby & Darby PC, December 26, 2002: US20020198412-A1

A cooling sensate compound having the general formula (I): 1 wherein n is an integer from 2 to 6. The compound is effective in imparting a refreshing and cooling sensation of long duration. A cooling sensate composition having the general formula (I) is used in a variety of formulations to impart th ...