1
Tetsuro Kamiya, Shigeyuki Echigo, Takehisa Matsuda, Ryuichiro Yoda, Nobuko Satoh: Closing plug of a defect for medical use and a closing plug device utilizing it. Nippon Zeon, Frishauf Holtz Goodman & Woodward, March 9, 1993: US05192301 (853 worldwide citation)

The closing plug and the closing plug device are used for closing a body defect percutaneously. During the insertion into the defect, the closing plug can be deformed to a smaller size to facilitate the insertion operation and recovered to its original larger shape after it is fitted to the defect, ...


2
Takehisa Matsuda, Hiroo Iwata, Tetsuo Itoh: Surgical adhesive. Sanyo Chemical, Oblon Fisher Spivak McClelland & Maier, April 26, 1988: US04740534 (68 worldwide citation)

Elastomeric or flexible surgical adhesives, comprising [A] NCO-terminated hydrophilic urethane prepolymer derived from hydrophilic polyether polyol of higher oxyethylene content, or combination of [A] with [B] unsaturated cyano compound containing cyano group attached to a carbon atom constituting t ...


3
Takehisa Matsuda, Teruo Takakura, Tetsuo Itoh: Surgical adhesive. Asahi Glass, Sanyo Chemical, Oblon Spivak McClelland Maier & Neustadt, February 19, 1991: US04994542 (58 worldwide citation)

Elastomeric or flexible surgical adhesives, comprising (i) a NCO-terminated hydrophilic urethane prepolymer derived from a fluorine-containing polyisocyanate and a hydrophilic polyether polyol of higher oxyethylene content, or a combinatioin of (i) with (ii) an unsaturated cyano compound containing ...


4
Hiroo Iwata, Sen Yamagata, Waro Taki, Takehisa Matsuda, Haruhiko Kikuchi, Yasuhiro Yonekawa, Yasuhiro Goto: Method of and apparatus for separating a balloon in a balloon catheter. Kabushiki Kaisha Tokai Rika Denki Seisakusho, Venable Baetjer and Howard, July 31, 1990: US04944746 (57 worldwide citation)

An apparatus for separating a balloon from a catheter member of a balloon is capable of melting and breaking a heat-meltable connecting member through which the balloon is connected to the catheter body by causing an electric current to flow between at least a pair of electrodes arranged on or in th ...


5
Tetsuo Itoh, Takehisa Matsuda: Surgical adhesive. Sanyo Chemical, Oblon Spivak McClelland Maier & Neustadt, December 22, 1992: US05173301 (54 worldwide citation)

Surgical adhesives, comprising an NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate and a polyol component comprising a polyester polyol derived from an electron-attracting group-containing dicarboxylic acid, such as 2-ketoglutaric acid, are capable of being easil ...


6
Takehisa Matsuda, Kazuhiko Inoue, Nobutaka Tani: Control of cell arrangement. Kanegafuchi Kagaku Kogyo Kabushiki Kaisha, Armstrong Westerman Hattori McLeland & Naughton, April 13, 1993: US05202227 (50 worldwide citation)

A device for controlling cell arrangement having a pattern composed of a cell adhesive surface and a cell non-adhesive surface, which has a good selectivity of cell adhesion and which can provide a fine pattern of cells in high resolution by culturing cells in a usual manner. The device is prepared ...


7
Takehisa Matsuda, Yasuhide Nakayama, Takashi Sugawara: Immobilization of an anti-thrombogenic substance with a photo-reactive azide and a photo-crosslinking material. K K Vayu, Davis Bujold & Streck, September 20, 1994: US05348873 (48 worldwide citation)

An anti-thrombogenic substance is immobilized on a base of a medical device to impart anti-thrombogenic properties to the medical device. The method comprises the steps of applying a photo-reactive azide derivative macromolecular material to a base to form a bonding layer, coating the bonding layer ...


8
Takehisa Matsuda, Minoo J Moghaddam, Katsukiyo Sakurai: Photocurable glycosaminoglycan derivatives, crosslinked glycosaminoglycans and method of production thereof. Seikagaku Kogyo Kabushiki Kaisha, Sughrue Mion Zinn Macpeak & Seas, October 31, 1995: US05462976 (47 worldwide citation)

Photocurable glycosaminoglycan (GAG) derivatives and crosslinked glycosaminoglycans, which are highly safe and biocompatible, a method of preparing such photocurable GAG derivatives readily moldable by casting using a solvent when desired, by which method unreacted substances causative of adverse ef ...


9
Takehisa Matsuda, Tetsuo Itoh, Tohru Tani: Surgical adhesive sheet, surgical instruments and methods of using the same. Sanyo Chemical, Oblon Spivak McClelland Maier & Neustadt, October 10, 1995: US05457141 (43 worldwide citation)

A sheet material, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer, is used for bonding of tissues, with improved handleability.


10
Takehisa Matsuda, Hiroo Iwata, Tetsuo Itoh: Surgical adhesive. Sanyo Chemical, Oblon Fisher Spivak McClelland & Maier, February 21, 1989: US04806614 (38 worldwide citation)

Elastomeric or flexible surgical adhesives, comprising [A] NCO-terminated hydrophilic urethane prepolymer derived from hydrophilic polyether polyol of higher oxyethylene content, or combination of [A] with [B] unsaturated cyano compound containing cyano group attached to a carbon atom constituting t ...