1
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, September 13, 1983: US04404183 (106 worldwide citation)

Sustained release pharmaceutical compositions of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


2
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan and Wayne, August 10, 1982: US04343789 (101 worldwide citation)

Sustained release pharmaceutical composition of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


3
Yutaka Konno, Mitsuo Mitomi, Takashi Sonobe, Shumpei Yamaguchi: Plaster structural assembly for iontophoresis. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, June 27, 1989: US04842577 (77 worldwide citation)

A novel plaster structural assembly is provided for iontophoresis wherein th e assembly is comprised of an electrode layer and a medicament-containing layer in which a water supplying layer is disposed between the electrode layer and the medicament-containing layer with a sealing cover disposed on t ...


4
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Patch. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, August 11, 1987: US04685911 (75 worldwide citation)

A patch having good transdermal property which utilizes a suppository base e.g. triglyceride of a vegetable saturated fatty acid having 12 to 18 carbon atoms together with a penetration enhancer.


5
Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Takashi Sonobe, Satoru Yoneya, Chiharu Sone: Sustained release pharmaceutical composition of solid medical material. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, June 16, 1987: US04673564 (49 worldwide citation)

Sustained release pharmaceutical compositions of a solid medical material which contains an amorphous solid medical material, polyethylene oxide, and at least one basic substance selected from the group consisting of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, methyl cellulose, polyvinyl ...


6
Seiya Kagatani, Shunji Hasumi, Takashi Sonobe, Masayoshi Aruga: Pharmaceutical compositions for nasal administration comprising calcitonin and an absorption-promoting substance. Yamanouchi Pharmaceutical Co, Burgess Ryan and Wayne, September 1, 1987: US04690952 (33 worldwide citation)

Pharmaceutical compositions for intranasal administration comprising (a) calcitonin and (b) at least one absorption enhancer selected from the group consisting of benzyl alcohol, ethanol, thiamine or a salt thereof, salicylic acid or a salt thereof, capric acid or a salt thereof, Macrogol 400, pyrid ...


7
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Patch. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, November 7, 1989: US04879119 (29 worldwide citation)

A patch having good transdermal property which utilizes a suppository base e.g. triglyceride of a vegetable saturated fatty acid having 12 to 18 carbon atoms together with a penetration enhancer.


8
Yutaka Konno, Hiroitsu Kawata, Masayoshi Aruga, Takashi Sonobe, Mitsuo Mitomi: Transdermal formulation of nicardipine hydrochloride. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, January 20, 1987: US04637930 (20 worldwide citation)

A formulation is provided for the transdermal administration of nicardipine hydrochloride. The formulation is comprised of nicardipine hydrochloride dissolved or suspended in a mixed liquid composed of an urea and at least one compound selected from the group consisting of propylene glycol, a monohy ...


9
Seiya Kagatani, Shunji Hasumi, Takashi Sonobe, Masayoshi Aruga: Pharmaceutical compositions comprising calcitonin and an absorption-promoting substance. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, November 29, 1988: US04788221 (17 worldwide citation)

Pharmaceutical compositions for intranasal administration comprising (a) calcitonin and (b) at least one absorption enhancer selected from the group consisting of benzyl alcohol, ethanol, thiamine or a salt thereof, salicylic acid or a salt thereof, capric acid or a salt thereof, Macrogol 400, pyrid ...


10
Takashi Sonobe, Hiroitsu Kawata, Masayoshi Aruga, Tadayoshi Ohmura, Satoru Yoneya, Chiharu Yamada, Yukio Kubota: Composition for long acting nicardipine preparation and process of producing the composition. Yamanouchi Pharmaceutical, Burgess Ryan & Wayne, July 19, 1988: US04758437 (10 worldwide citation)

A spherical pellet like composition of nicardipine composed of small granular nuclei such as sugar particles coated with amorphous nicardipine or a salt thereof, a pH-dependent additive and a surface active agent. The spherical pellet like composition of nicardipine may have a further coating of a m ...



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