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Masanobu Shinoda, Eita Emori, Fumiyoshi Matsuura, Toshihiko Kaneko, Norihito Ohi, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Sadakazu Miyashita, Taro Hibara, Takashi Seiki, Richard Clark, Hitoshi Harada: Carboxylic acid derivatives and drugs containing the same. Eisai, Birch Stewart Kolasch & Birch, April 26, 2005: US06884821 (23 worldwide citation)

Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydrogen, hydroxyl, alkyl, or the like; L is a sin ...


2
Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Tohru Arai: Methods of affecting feeding and weight in mammals by administration of relaxin-3. Eisai R&D Managment, Wenderoth Lind & Ponack L, December 29, 2009: US07638490 (1 worldwide citation)

Relaxin-3 is found to have feeding-stimulating activity, body weight increasing activity, and fat weight increasing activity when intracerebroventricularly administered to rats through observation of amount of feeding, body weight and fat weight after administration of relaxin-3. This invention incl ...


3
Tetsu Kawano, Junro Kuromitsu, Akiko Hamaguchi, Keiko Yamaguchi, Takashi Seiki, Kazuma Takase: Methods for identifying GPR83 agonists and GPR83 antagonists capable of modulating regulatory T cell function. Eisai R&D Management, Lahive & Cockfield, May 31, 2007: US20070122845-A1

The present invention provides methods for identifying a GPR83 agonist capable of stimulating a regulatory T cell function and methods for identifying a GPR83 antagonist capable of suppressing a regulatory T cell function.


4
Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Tohru Arai: Screening method. Wenderoth Lind & Ponack, March 8, 2007: US20070054850-A1

The present inventors have found that relaxin-3 has a feeding-stimulating activity, a body weight increasing activity, and fat weight increasing activity by intracerebroventricularly administering relaxin-3 to rats and observing the amount of feeding, body weight and fat weight, and so on after the ...


5
Takayuki Hida, Tomoko Sekiya, Toru Sawai, Takashi Seiki, Eiki Takahashi, Michiko Kosasa, Kokichi Harada, Toru Arai: Screening method. Wenderoth Lind & Ponack, July 1, 2010: US20100168014-A1

The present inventors have found that relaxin-3 has a feeding-stimulating activity, a body weight increasing activity, and fat weight increasing activity by intracerebroventricularly administering relaxin-3 to rats and observing the amount of feeding, body weight and fat weight, and so on after the ...


6
Nakakuki Hideki, Takashi Seiki, Kaneda Hidenori: Method for inspecting printed matter. Toppan Printing, October 9, 1998: JP1998-269357

PROBLEM TO BE SOLVED: To automatically inspect a printed matter without performing positioning (registering) manually even if the position of a printed matter to be inspected is roughly inputted. SOLUTION: A sample image that becomes a comparison reference is stored in reference image memory (S1), a ...


7
Nakakuki Hideki, Takashi Seiki, Kaneda Hidenori: Method and device for inspecting printed matter. Toppan Printing, October 9, 1998: JP1998-269359

PROBLEM TO BE SOLVED: To provide an inspection method which detects stain, defect, a wrong character, etc., for a printed matter by comparing it with a reference design signal for each corresponding pixel that is preliminarily inputted. SOLUTION: (1) An inspection sample image is stored in reference ...


8
Takashi Seiki, Takahashi Jun, Ogawa Keiji: Method and device for retrieving kanji font data. Toppan Printing, April 13, 2001: JP2001-101174

PROBLEM TO BE SOLVED: To provide a KANJI (Chinese character) font data retrieving method and its device which can easily retrieve or prepare external character font data. SOLUTION: This KANJI font data retrieving method which stores various information about KANJI and the KANJI font data in a storag ...


9
Nakakuki Hideki, Takashi Seiki, Kaneda Hidenori: Check method and device for printed matter. Toppan Printing, October 27, 1998: JP1998-289311

PROBLEM TO BE SOLVED: To check a printed matter even when its positioning is rough or the form is elastic when the printed matter image is compared with a sample image to detect the stains, the breakage, the wrong characters, etc., of the printed matter. SOLUTION: A check sample and the image of a p ...