1
Hickey Eugene R, Liu Weimin, Sun Sanxing, Ward Yancey David, Young Erick Richard Roush: Cathepsin s inhibitors. Boehringer Ingelheim Pharmaceuticals, Hickey Eugene R, Liu Weimin, Sun Sanxing, Ward Yancey David, Young Erick Richard Roush, RAYMOND Robert P, September 30, 2004: WO/2004/083182 (11 worldwide citation)

This invention relates to peptidyl compounds of the formulas (I) and (II) active as cathepsin S, a cysteine protease, inhibitors. The compounds are selective, reversible inhibitors of the cathepsin S are therefore useful in the treatment of autoimmune and other diseases. The invention also relates t ...


2

3
Breitfelder Steffen, Cirillo Pier F, Hao Ming Hong, Hickey Eugene R, Sharma Rajiv, Sun Sanxing, Takahashi Hidenori: Urea derivatives as anti-inflammatory agents. Boehringer Ingelheim Pharmaceuticals, Breitfelder Steffen, Cirillo Pier F, Hao Ming Hong, Hickey Eugene R, Sharma Rajiv, Sun Sanxing, Takahashi Hidenori, RAYMOND Robert, May 25, 2001: WO/2001/036403 (2 worldwide citation)

Disclosed are novel aromatic compounds of formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of mak ...


4
Betageri Rajashehar, Breitfelder Steffen, Cirillo Pier F, Gilmore Thomas A, Hickey Eugene R, Kirrane Thomas M, Moriak Monica H, Moss Neil, Patel Usha R, Proudfoot John R, Regan John R, Sharma Rajiv, Sun Sanxing, Swinamer Alan D, Takahashi Hidenori: Heterocyclic urea and related compounds useful as anti-inflammatory agents. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert, September 21, 2000: WO/2000/055139 (1 worldwide citation)

Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.


5
Cywin Charles L, Chen Zhidong, Emeigh Jonathan, Fleck Roman Wolfgang, Hao Ming Hong, Hickey Eugene, Liu Weimin, Marshall Daniel Richard, Morwick Tina, Nemoto Peter, Sorcek Ronald John, Sun Sanxing, Wu Jiang Ping: 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amides. Boehringer Ingelheim Pharma, December 31, 2008: EP2008654-A1

Disclosed are compounds of formula (I): wherein R 1 and R 2 are defined herein, which are useful as inhibitors of the kinase activity of the I B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and ...


6
Betageri Rajashekhar, Breitfelder Steffen Dr, Cirillo Pier Francesco, Gilmore Thomas A, Hickey Eugene Richard, Kirrane Thomas Jr, Moriak Monica Helen, Moss Neil, Patel Usha R, Proudfoot John R, Regan John Robinson, Sharma Rajiv, Sun Sanxing, Swinamer Alan D, Takahashi Hidenori: Heterocyclic urea and related compounds useful as anti-inflammatory agents. Boehringer Ingelheim Pharma, October 13, 2004: EP1466906-A1

Disclosed are novel aromatic compounds which are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.


7
Betageri Rajashekhar, Breitfelder Steffen, Cirillo Pier Francesco, Gilmore Thomas A, Hickey Eugene Richard, Kirrane Thomas, Moriak Monica Helen, Moss Neil, Patel Usha R, Proudfoot John R, Regan John Robinson, Sharma Rajiv, Sun Sanxing, Swinamer Alan D, Takahashi Hidenori: Heterocyclic urea and related compounds useful as anti-inflammatory agents. Boehringer Ingelheim Pharma, August 16, 2006: EP1690854-A1

Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.


8

9

10