1
Stuart K Williams, Bruce E Jarrell: Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, April 11, 1989: US04820626 (166 worldwide citation)

The present invention provides a novel method of treating a synthetic or naturally occurring implant, such as a vascular graft, intended for implantation in a human patient, comprising obtaining human microvascular rich tissue from that patient; separating microvascular endothelial cells from that t ...


2
Stuart K Williams, Bruce E Jarrell: Method of treating a synthetic naturally occurring surface with a collagen laminate to support microvascular endothelial cell growth, and the surface itself. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, July 21, 1992: US05131907 (117 worldwide citation)

A novel implantable prosthesis for implantation in human patients is disclosed which comprises a synthetic substrate and a Type IV/V collagen surface layer seeded with a confluent monolayer of autologous endothelial cells. In the preferred embodiment, a base layer of interstitial collagen is adhered ...


3
Stuart K Williams, Robert Snyder: Glaucoma shunt and a method of making and surgically implanting the same. The Arizona Board of Regents, Oblon Spivak McClelland Maier & Neustadt P C, March 2, 2004: US06699210 (114 worldwide citation)

A glaucoma shunt including first and second porous regions laminated together, and a third region having edge areas fused to edge areas of the second region so as to form a hollow reservoir therebetween. Also included is a catheter having a first end sandwiched between the second and third regions a ...


4
Stuart K Williams, Bruce E Jarrell: Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, May 13, 1997: US05628781 (112 worldwide citation)

Implant materials having porosity are provided by the present invention. Methods for treating a synthetic or naturally occurring implant, such as a vascular graft, intended for implantation in a human patient are also provided comprising obtaining human microvascular fat tissue, homogenizing the fat ...


5
Paul G Alchas, Alfred W Prais, Bruce E Jarrell, Stuart K Williams, Joseph A DiPisa Jr: Device and method for collecting and processing fat tissue and procuring microvessel endothelial cells to produce endothelial cell product. Woodcock Washburn Kurtz Mackiewicz & Norris, December 13, 1994: US05372945 (106 worldwide citation)

Methods and apparatus for collecting and processing tissue to produce an endothelial cell product having a vessel for rinsing, draining, digesting and isolating tissue. The vessel has a rinsing and digesting chamber for containing tissue during processing. An inlet in the rinsing and digesting chamb ...


6
Paul G Alchas, Frank A Augello, Christopher J Brooks, Tony A Cutshall, Joseph A DiPisa Jr, Stuart K Williams, Jonathan B Gabel, Paul J Mulhauser, Wes Prais, Bruce E Jarrell, Deborah G Rose: Endothelial cell procurement and deposition kit. Thomas Jefferson University, Becton, Woodcock Washburn Kurtz Mackiewicz & Norris, July 30, 1991: US05035708 (93 worldwide citation)

The invention is an endothelial cell procurement and deposition kit for collecting fat from a patient, processing said fat to produce an endothelial cell deposition product, and depositing said product on the surface of a graft, all under sterile conditions established and maintained within the comp ...


7
R Anthony Carabasi, Bruce E Jarrell, Stuart K Williams: Method of reendothelializing vascular linings. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, November 28, 1989: US04883755 (54 worldwide citation)

A method for treating the vascular passage of a patient, damaged by procedures such as an endarterectomy which denude portions of the vascular passages of their endothelial cell linings, is disclosed. In this method, endothelial cells are isolated from the patient's own microvessels, the flow of blo ...


8
Stuart K Williams, Bruce E Jarrell: Implantable prosthetic device for implantation into a human patient having a surface treated with microvascular endothelial cells. Thomas Jefferson University, Woodcock Washburn Kurtz Mackiewicz & Norris, July 27, 1993: US05230693 (41 worldwide citation)

The present invention provides a synthetic or naturally occurring implant, such as a vascular graft, for implantation into a human patient. Uncultured, microvascular endothelial cells, isolated from microvascular endothelial cell rich tissue are disposed on at least one surface of the implant to pro ...


9
Paul G Alchas, Frank A Augello, Christopher J Brooks, Tony A Cutshall, Joseph A DiPisa Jr, Stuart K Williams, Jonathan B Gabel, Paul J Mulhauser, Wes Prais, Bruce E Jarrell, Deborah G Rose: Endothelial cell procurement and deposition kit. Thomas Jefferson University, Becton Dickinson and Company, Woodcock Washburn Kurtz Mackiewicz & Norris, May 17, 1994: US05312380 (38 worldwide citation)

The invention is an endothelial cell procurement and deposition kit for collecting fat from a patient, processing said fat to produce an endothelial cell deposition product, and depositing said product on the surface of a graft, all under sterile conditions established and maintained within the comp ...


10
Paul G Alchas, Jonathan B Gabel, Stuart K Williams, Bruce E Jarrell, Deborah G Rose, Pauline K Park, Thomas L Carter, Frank A Augello, Joseph A DiPisa Jr: Endothelial cell deposition device. Thomas Jefferson University, Becton Dickinson and Company, Woodcock Washburn Kurtz Mackiewicz & Norris, August 15, 1995: US05441539 (20 worldwide citation)

Apparatus for depositing a cell product, such as endothelial cell product, in a graft and inserting the graft in a vessel is disclosed. The apparatus preferably comprises a tunneler tube that has a hollow portion for supporting the graft therein, apertures to permit the flow of cell product, and a p ...