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Seiwert Scott, Beigelman Leonid, Buckman Brad, Stoycheva Antitsa Dimitrova, Porter Steven B, Bradford Williamson Ziegler, Serebryany Vladimir: Novel macrocyclic inhibitors of hepatitis c virus replication. Intermune, Seiwert Scott, Beigelman Leonid, Buckman Brad, Stoycheva Antitsa Dimitrova, Porter Steven B, Bradford Williamson Ziegler, Serebryany Vladimir, Mallon Joseph J, November 26, 2009: WO/2009/142842 (25 worldwide citation)

The embodiments provide compounds of the general Formulae I, II, EI, IV, V, VI, VII, and X, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection an ...


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Buckman Brad O, Wang Guangyi, Beigelman Leonid, Stoycheva Antitsa Dimitrova: Novel inhibitors of hepatitis c virus replication. Intermune, Buckman Brad O, Wang Guangyi, Beigelman Leonid, Stoycheva Antitsa Dimitrova, MALLON Joseph J, November 5, 2009: WO/2009/134616 (10 worldwide citation)

The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibr ...


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Beigelman Leonid, Buckman Brad, Wang Guangyi, Matulic adamic Jasenka, Stoycheva Antitsa Dimitrova, Andrews Steven W, Misialek Shawn Maurice, Rajagopalan P T Ravi, Fryer Andrew M, Gunawardana Indrani, Haas Julia: Novel inhibitors hepatitis c virus replication. Intermune Array Biopharma, Meng Dui, March 31, 2010: CN200880010161

The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection, the methods generally involving a ...