1
Gordon Elger, Stewart T Leslie, Sandra T A Malkowska, Ronald B Miller, Philip J Neale: Controlled release pharmaceutical composition. Euroceltique, Steinberg & Raskin, May 30, 1989: US04834985 (219 worldwide citation)

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C.sub.12 -C.sub.36 fatty alcohol and a poly ...


2
Gordon A Elger, Stewart T Leslie, Sandra T A Malkowska, Ronald B Miller, Philip J Neale: Controlled release pharmaceutical composition. Euroceltique, Steinberg & Raskin, May 9, 1989: US04828836 (199 worldwide citation)

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a controlled release matrix comprising a water soluble polydextrose.


3
Robert S Goldie, Sandra T A Malkowska, Stewart T Leslie, Ronald B Miller: Controlled release hydromorphone composition. Euroceltique, Steinberg & Raskin, July 4, 1989: US04844909 (175 worldwide citation)

A solid controlled release, oral dosage form, the dosage form comprising a therapeutically effective amount of hydromorphone or a salt thereof in a matrix wherein the dissolution rate in vitro of the dosage form, when measured by the USP Paddle Method at 100 rpm in 900 ml aqueous buffer (pH between ...


4
Robert S Goldie, Sandra T A Malkowska, Stewart T Leslie, Ronald B Miller: Controlled release hydromorphone composition. Euroceltique, Steinberg & Raskin, February 5, 1991: US04990341 (161 worldwide citation)

A solid controlled release, oral dosage form, the dosage form comprising a therapeutically effective amount of hydromorphone or a salt thereof in a matrix wherein the dissolution rate in vitro of the dosage form, when measured by the USP Paddle Method of 100 rpm in 900 ml aqueous buffer (pH between ...


5
Robert S Goldie, Sandra T A Malkowska, Stewart T Leslie, Ronald B Miller: Controlled release dihydrocodeine composition. Euroceltique, Steinberg & Raskin, May 30, 1989: US04834984 (161 worldwide citation)

A solid controlled release, oral dosage form, the dosage form comprising an analgesically effective amount of dihydrocodeine or a salt thereof in a controlled release matrix wherein the dissolution rate in vitro of the dosage form, when measured by the USP Paddle Method at 100 rpm in 900 ml aqueous ...


6
Benjamin Oshlack, Stewart T Leslie: Extended action controlled release compositions. Euroceltique, Steinberg & Raskin, April 17, 1984: US04443428 (139 worldwide citation)

The action of controlled release medications is extended by incorporation into the controlled release matrix for a medication a mixture of the salt form of the medication with the free base form of the medication in a proportion of a 75-25% by weight of the salt form to 25-75% by weight of the free ...


7
Gordon A Elger, Stewart T Leslie, Sandra T A Malkowska, Ronald B Miller, Philip J Neale: Pharmaceutical composition comprising analgesic and anti-inflammatory agent. Euroceltique, Steinberg & Raskin, July 4, 1989: US04844907 (136 worldwide citation)

A pharmaceutical composition in the form of a multiphase (especially a bilayered, optionally coated) tablet. The tablet has a narcotic analgesic phase containing a therapeutically effective quantity of a narcotic analgesic or an analgesically effective salt thereof (e.g. codeine phosphate) and a non ...


8
Anthony W Jenkins, Stewart T Leslie, Ronald B Miller: Oral pharmaceutical composition through mucosa. Euroceltique, Steinberg & Raskin, July 10, 1990: US04940587 (119 worldwide citation)

An arrangement is provided for the application of an oral pharmaceutical to the mucosa of the oral or nasal cavity, for sustained release there of the drug. The arrangement of the invention comprises a body which has a size and shape suitable for insertion into and retention in the oral or nasal cav ...


9
Ronald B Miller, Stewart T Leslie, Sandra T A Malkowska, Kevin J Smith, Walter Wimmer, Horst Winkler, Udo Hahn, Derek A Prater: Controlled release formulation. Euro Celtique, Steinberg Raskin & Davidson P C, January 7, 1997: US05591452 (106 worldwide citation)

A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.


10
Ian R Buxton, Helen Critchley, Stewart T Leslie, Derek A Prater, Ronald B Miller, Sandra T A Malkowska: Pharmaceutical spheroid formulation. Euro Celtique, Steinberg Raskin & Davidson P C, February 11, 1997: US05601845 (103 worldwide citation)

A controlled release composition including spheroid cores of diltiazem. or a pharmaceutically acceptable salt thereof and optionally a spheronizing agent, the cores being coated with a controlled release layer, and a method of manufacturing the same, is disclosed. The spheronizing agent when present ...



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