1
David R Walt, Steven M Barnard: Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample. Trustees of Tufts College, David Prashker, September 14, 1993: US05244636 (235 worldwide citation)

The present invention provides a unique fiber optic sensor which is able to conduct multiple assays and analysis concurrently using a plurality of different dyes immobilized at individual spatial positions on the surface of the sensor. The present invention also provides apparatus for making precise ...


2
David R Walt, Steven M Barnard: Fiber optic array sensors, apparatus, and methods for concurrently visualizing and chemically detecting multiple analytes of interest in a fluid sample. Trustees of Tufts College, David Prashker, June 14, 1994: US05320814 (190 worldwide citation)

The present invention provides a unique fiber optic sensor which is able to provide a viewing zone for visual examination of a sample and its surrounding environment; and is able to conduct multiple assays concurrently using a plurality of different dyes immobilized at individual spatial positions w ...


3
David R Walt, Steven M Barnard: Method of making imaging fiber optic sensors to concurrently detect multiple analytes of interest in a fluid sample. Trustees of Tufts College, David Prashker, October 5, 1993: US05250264 (189 worldwide citation)

The present invention provides a unique fiber optic sensor which is able to conduct multiple assays and analyses concurrently using a plurality of different dyes immobilized at individual spatial positions on the surface of the sensor. The present invention also provides apparatus for making precise ...


4

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Mark S Chee, Steven M Barnard, Chanfeng Zhao: Encoding and decoding of array sensors utilizing nanocrystals. Illumina, Robin M Silva, David C Foster, Dorsey & Whitney, April 8, 2003: US06544732 (159 worldwide citation)

Described herein are assays and components for encoding and decoding microspheres. Each assay or component described utilizes at least one nanocrystal.


6
Todd A Dickinson, Shawn Meade, Steven M Barnard, Anthony W Czarnik, James Bierle, Bahram G Kermani, Mark S Chee: Array compositions for improved signal detection. Illumina, Knobbe Martens Olson & Bear, September 13, 2005: US06942968 (65 worldwide citation)

The invention relates methods of improving signal detection from an array and methods for background subtraction in an array. The invention provides for novel array compositions including arrays with wells with different shapes, or surfaces coated with reflective or selectively absorptive coatings. ...


7
Michal Lebl, Mark S Chee, Steven M Barnard, David L Heiner, Vit Pokorny, Mark J Nibbe, Aaron Christopher Jones: Oligonucleotide synthesizer. Illumina, Dorsey & Whitney, December 16, 2003: US06663832 (38 worldwide citation)

An apparatus for high-throughput combinatorial syntheses of organic molecules including a reaction vessel for containing a combinatorial-chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress ...


8
Mark S Chee, Steven M Barnard, Chanfeng Zhao: Encoding and decoding of array sensors utilizing nanocrystals. Illumina, Robin M Silva Esq, David C Foster Esq, Dorsey & Whitney, May 10, 2005: US06890764 (25 worldwide citation)

Described herein are assays and components for encoding and decoding microspheres. Each assay or component described utilizes at least one nanocrystal.


9
John R Stuelpnagel, David L Barker, Jorge Velarde Jr, Steven M Barnard, Michael Graige: Compositions and methods for representational selection of nucleic acids from complex mixtures using hybridization. Illumina, Brent C Moore, Illumina, December 23, 2014: US08916350 (2 worldwide citation)

The invention provides a method of selecting a representational sample of nucleic acid sequences from a complex mixture. The method includes: (a) contacting a complex mixture of nucleic acids under conditions sufficient for hybridization with a population of capture probes complementary to one or mo ...


10
Steven M Barnard, M Shane Bowen, Maria Candelaria Rogert Bacigalupo, Wayne N George, Andrew A Brown, James Tsay: Gel patterned surfaces. Illumina, Illumina, December 6, 2016: US09512422 (1 worldwide citation)

Provided is an array including a solid support having a surface, the surface having a plurality of wells, the wells containing a gel material, the wells being separated from each other by interstitial regions on the surface, the interstitial regions segregating the gel material in each of the wells ...