1
Amish Desai, Xing Yang, Yu Chong Tai, Elaine Marzluff, Dirk Bockenkamp, Stephen Mayo: Microfluidic sub-millisecond mixers. California Institute of Technology, Fish & Richardson P C, July 13, 1999: US05921678 (139 worldwide citation)

A micromachined, high Reynolds number, sub-millisecond liquid mixer for the study of chemical reaction kinetics. This bulk micromachined silicon mixer is capable of initiating and quenching chemical reactions in intervals as short as 100 .mu.s. The mixer chip contains two tee mixers connected by one ...


2
Stephen Mayo, Julia Shifman, Motomu Shimaoka, Timothy Springer: Proteins with integrin-like activity. California Institute of Technology, Robin M Silva Esq, Renee M Kosslak Esq, Dorsey & Whitney, October 4, 2005: US06951927

The invention relates to novel proteins with novel integrin and I domain activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of integrin related disorders. TABLE 1 Computationally designed mutantsa WT ido1q ido1r ido2r j ...


3
Niles Pierce, D Benjamin Gordon, Stephen Mayo: Methods and compositions utilizing hybrid exact rotamer optimization algorithms for protein design. Robin M Silva Esq, Flehr Hohbach Test Albritton & Herbert, May 2, 2002: US20020052004-A1

The present invention relates to an apparatus and method for quantitative protein design and optimization. In particular, the invention describes the use of Hybrid Exact Rotamer Optimization algorithms in protein design.


4
Stephen Mayo, Daniel N Bolon: Method for the generation of proteins with new enzymatic function. Robin M Silva Esq, Flehr Hohbach Test Albritton & Herbert, December 5, 2002: US20020183937-A1

The invention relates to the use of a variety of computational methods for generating enzyme-like protein catalysts. Specifically, computational methods are used to insert active site domains, including catalytic domains and binding domains, into a protein scaffold and optimize surrounding amino aci ...


5
Stephen Mayo, Julia Shifman, Motomu Shimaoka, Timothy Springer: Novel proteins with integrin-like activity. Flehr Hohbach Test Albritton & Herbert, March 20, 2003: US20030054440-A1

The invention relates to novel proteins with novel integrin and I domain activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of integrin related disorders.


6
D Benjamin Gordon, Geoffrey K Hom, Stephen Mayo, Niles Pierce: Methods and compositions utilizing hybrid exact rotamer optimization algorithms for protein design. Flehr Hohbach Test Albritton & Herbert, March 13, 2003: US20030049680-A1

The present invention relates to an apparatus and method for quantitative protein design and optimization. In particular, the invention describes the use of Hybrid Exact Rotamer Optimization algorithms in protein design.