1
Wallace C Snipes, Stephen J Wagner: Erodible matrix for sustained release bioactive composition. Zetachron, Vorys Sater Seymour and Pease, February 21, 1989: US04806337 (148 worldwide citation)

A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of (a.) 5% to 95% by weight of a solid water-dispersible polyether diol havin ...


2
Wallace C Snipes, Stephen J Wagner: Erodible matrix for sustained release bioactive composition. Zetachron, Vorys Sater Seymour and Pease, May 17, 1988: US04744976 (79 worldwide citation)

A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises the biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of


3
Stephen J Wagner: Inactivation of extracellular enveloped viruses in blood and blood components by phenthiazin-5-ium dyes plus light. The American National Red Cross, Sterne Kessler Goldstein & Fox, August 13, 1996: US05545516 (47 worldwide citation)

This invention provides methods for inactivating pathogenic contaminants in whole blood, plasma, cellular blood components, or in any combination thereof, by adding a phenthiazin-5-ium dye(s) thereto and irradiating said dye-containing composition for an effective length of time with light of wavele ...


4
Stephen J Wagner, Louis Cincotta: Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light. The American National Red Cross, The Rowland Institute for Science, Sterne Kessler Goldstein & Fox P L L C, February 29, 2000: US06030767 (26 worldwide citation)

This invention is directed to a method for inactivating pathogenic contaminants, such as viruses, bacteria, parasites and leukocytes, frequently found in whole blood or blood components, such as red blood cells or plasma, which comprises treating whole blood or blood components with an amphiphilic p ...


5
Stephen J Wagner, Andrew Myrup, Christina Celluzzi: Method for enriching adherent monocyte populations. American National Red Cross, Buchanan Ingersoll & Rooney PC, July 1, 2008: US07393628 (10 worldwide citation)

The present invention provides methods and apparatus for the rapid and efficient collection and purification of activated monocytes. The methods and apparatus of the present invention provide means for effecting the collection and purification in an aseptic environment. The method involves filtering ...


6
Wallace C Snipes, Stephen J Wagner: Controlled release potassium chloride composition. Zetachron, Smith & Schnacke, May 23, 1989: US04832955 (7 worldwide citation)

The invention is directed to a pharmaceutical composition comprising a microencapsulated potassium salt encapsulated in a shell wall consisting essentially of from about 85% to about 97% ethyl cellulose and from about 3% to about 15% of an amphiphile based on the weight of the shell wall; wherein th ...


7
Mark Seaver, James C Crookston, Stephen J Wagner: Automated epifluorescence microscopy for detection of bacterial contamination in platelets. The United States of America represented by the Secretary of the Navy, John J Karasek, Stephen T Hunnius, October 12, 2004: US06803208 (4 worldwide citation)

A method for determining the presence of bacteria in a platelet or red blood cell sample is disclosed. The method includes the steps of: lysing a substantial portion of the platelets or red blood cells; staining the bacteria using a membrane permeable nucleic acid stain; filtering the sample using a ...


8
Stephen J Wagner, Barbara B Myrvaagnes: Electronic circuit assembly having high contrast fiducial. ITT Manufacturing Enterprises, RatnerPrestia, February 15, 2005: US06855953

An electronic circuit assembly having a fiducial on a lower layer substrate. The fiducial is viewed through a through hole that is aligned with the fiducial and extends through an upper layer substrate that is adjacent the lower layer substrate. The fiducial and the through hole provide a high contr ...


9
Stephen J Wagner: Disinfection of biological fluids using asymmetric cyanine dyes. American National Red Cross, Buchanan Ingersoll & Rooney PC, March 16, 2010: US07678538

Asymmetric cyanine dyes of Formula I bind nucleic acid but not red blood cell membrane, and function as photosensitizers when rigidly bound but not when free in solution. Unbound dye thus causes minimal oxidative damage. The dyes do not substantially accumulate in red blood cells, thereby minimizing ...


10
Stephen J Wagner, Andrey Skripchenko: Method of inactivating pathogens in a red blood cell-containing composition. The American National Red Cross, Sterne Kessler Goldstein & Fox Pllc, Attorneys at Law, November 29, 2001: US20010046662-A1

The invention provides a method for reducing the level of active pathogenic contaminants, such as viruses, bacteria and parasites, found in whole blood and blood components. The method comprises adding to a red blood cell-containing composition at least one phenothiazin-5-ium dye in an amount effect ...