1
Norman F Sheppard Jr, John T Santini Jr, Stephen J Herman, Michael J Cima, Robert S Langer, Dennis Ausiello: Microchip reservoir devices using wireless transmission of power and data. MicroCHIPS, Sutherland Asbill & Brennan, June 5, 2007: US07226442 (193 worldwide citation)

Devices, systems, and methods are provided for wirelessly powering and/or communicating with microchip devices used for the controlled exposure and release of reservoir contents, such as drugs, reagents, and sensors. In one embodiment, the system includes (1) a microchip device comprising a substrat ...


2
Scott A Uhland, Benjamin F Polito, Stephen J Herman, John T Santini Jr, John M Maloney: Methods for hermetically sealing microchip reservoir devices. MicroCHIPS, Sutherland Asbill & Brennan, December 7, 2004: US06827250 (190 worldwide citation)

Methods are provided for hermetically sealing the reservoirs of microchip devices and for hermetically sealing the substrate assemblies in a hermetic packaging structure. In one embodiment, the method comprises (1) providing a primary substrate having a front side and a back side, the substrate comp ...


3
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Apparatus for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, September 2, 1997: US05662712 (119 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...


4
Stephen J Herman, Laurence A Roth, Edward L Sinofsky, Douglas W Dickinson Jr: Wire guided laser catheter. C R Bard, Wolf Greenfield & Sacks, July 25, 1989: US04850351 (116 worldwide citation)

A catheter having optical fibers for delivering laser energy to a blood vessel to remove obstructions in the blood vessel is adapted to be guided controllably and selectively by a guide wire to the site to be treated. The catheter includes a central lumen which is open at the distal end of the cathe ...


5
Laurence A Roth, Stephen J Herman, Farhad Khosravi, David Melanson, Michael Dumont, Patrick K Campbell, John C Spiridigliozzi: Devices and methods for application of intraluminal photopolymerized gels. Focal, Wolf Greenfield & Sacks P C, July 14, 1998: US05779673 (113 worldwide citation)

Devices for providing polymeric layers on the interior surface of body lumens and spaces are disclosed. The devices can include proximal and distal occlusion elements to define the treatment space and an optical emitter to provide light for a photopolymerization procedure. The devices may include a ...


6
John T Santini Jr, Michael J Cima, Robert S Langer, Dennis Ausiello, Norman F Sheppard Jr, Stephen J Herman: Flexible microchip devices for ophthalmic and other applications. MicroCHIPS, Sutherland Asbill & Brennan, December 20, 2005: US06976982 (111 worldwide citation)

Microchip device arrays that can conform to a curved surface are provided for the controlled release or exposure of reservoir contents. The arrays comprise two or more microchip device elements, each of which includes a plurality of reservoirs that contain molecules for controlled release or compone ...


7
Barry M Yomtov, Stephen J Herman, John T Santini Jr: Medical device for neural stimulation and controlled drug delivery. MicroCHIPS, Sutherland Asbill & Brennan, October 6, 2009: US07599737 (100 worldwide citation)

Medical devices and methods are provided for electrical stimulation of neural tissue and controlled drug delivery to a patient. The device includes an implantable drug delivery module which comprises a plurality of reservoirs, a release system comprising at least one drug contained in each of the re ...


8
Stephen C Rowe, Jeffrey A Hubbell, Stephen J Herman, Vae Sun, Michael F Lang, George E Selecman, Frederick F Ahari: Apparatus and method for local application of polymeric material to tissue. Focal, Wolf Greenfield & Sacks P C, March 18, 1997: US05612050 (90 worldwide citation)

An apparatus is provided for applying to a surface of mammalian tissue including soft, living tissue an initially fluent material and then activating the material by exposure to an energy source. The material may be a liquid capable of polymerization to a non-fluent state by exposure to actinic ligh ...


9
Laurence A Roth, Stephen J Herman, Carl R Turnquist, Edward L Sinofsky, Jacob Y Wong: Catheter system for controlled removal by radiant energy of biological obstructions. C R Bard, Wolf Greenfield & Sacks, April 4, 1989: US04817601 (81 worldwide citation)

A catheter for delivering radiant energy, such as a laser beam, is used in a technique to controllably apply the radiant energy in a patient's body, such as in a blood vessel. The radiant energy is applied in a manner which erodes biological material and may be used to drill through vascular obstruc ...


10
Chandrashekhar P Pathak, Amarpreet S Sawhney, Jeffrey A Hubbell, Stephen J Herman, Laurence A Roth, Patrick K Campbell, Kevin M Berrigan, Peter K Jarrett, Arthur J Coury: Polymeric article for intraluminal photothermoforming. Focal, Wolf Greenfield & Sacks P C, April 21, 1998: US05741323 (80 worldwide citation)

A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed ...