1
Stephen B Haber: Antiinflammatory and/or analgesic 2,3-diaryl-5-silyl thiophenes. E I Du Pont de Nemours and Company, February 21, 1984: US04432974 (10 worldwide citation)

2,3-Diaryl-5-silyl thiophenes, such as 2,3-bis(4-methoxyphenyl)-5-(trimethylsilyl)thiophene; 2,3-bis(4-methoxyphenyl)-5-(ethenyldimethylsilyl)thiophene; and 2,3-bis(4-methoxyphenyl)-5-[(2-propenyl)dimethylsilyl]-thiophene, are useful in the treatment of inflammation and/or pain.


2
Stephen B Haber: Antiinflammatory 4,5-diaryl-.alpha.-(polyhalomethyl)-2-thiophenemethanols. E I Du Pont de Nemours and Company, April 26, 1983: US04381311 (9 worldwide citation)

4,5-Diaryl-.alpha.-(polyhalomethyl)-2-thiophenemethanols such as 4-(4-methoxyphenyl)-5-(4-methylthiophenyl)-.alpha.,.alpha.-bis(trifluorome thyl)-2-thiophenemethanol useful for treating arthritis and/or alleviating pain.


3
Stephen B Haber: 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea. E I Du Pont de Nemours and Company, April 11, 1989: US04820827 (9 worldwide citation)

A small group of 2,3-diaryl-5-bromothiophene compounds such as 5-bromo-2-(4-methylthiophenyl)-3-(4-fluorophenyl)thiophene have been found to possess significant and unexpected antiinflammatory activity, and inhibition of prostaglandin synthetase useful for the treatment of arthritis and dysmenorrhea ...


4
Stephen B Haber: Antiinflammatory 4,5-diaryl-.alpha.,.alpha.-bis (polyhalomethyl)-2-thiophenemethanamines. E I Du Pont de Nemours and Company, January 24, 1984: US04427693 (9 worldwide citation)

4,5-Diaryl-.alpha.,.alpha.-bis(polyhalomethyl)-2-thiophene-methanamines, such as 4,5-bis(4-fluorophenyl)-.alpha.,.alpha.-bis-(trifluoromethyl)-2-thiophenem ethanamine, useful for treating arthritis and/or alleviating pain.


5
Stephen B Haber: Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes. E I Du Pont de Nemours and Company, May 20, 1986: US04590205 (7 worldwide citation)

Certain 2,3-diaryl-5-halo thiophenes are useful in the treatment of inflammation and/or pain.


6
Stephen B Haber: Antiinflammatory and/or analgesic silylfurans. E I Du Pont de Nemours and Company, February 19, 1985: US04500520 (5 worldwide citation)

Silyldiarylfurans, such as 4,5-bis(4-methoxyphenyl)-2-trimethylsilylfuran, are useful in the treatment of inflammation and/or pain.


7
Stephen B Haber: Antiinflammatory and/or analgesic 5-alkylthiophenes. E I Du Pont de Nemours and Company, June 7, 1988: US04749712 (3 worldwide citation)

5-Alkyl-2,3-diarylthiophenes, such as 5-(1,1-dimethylethyl)-2,3-bis(4-methoxyphenyl)thiophene, 5-(1-methylpropyl)-2,3-bis(4-methoxyphenyl)thiophene and 5-cyclohexyl-2,3-bis(4-methoxyphenyl)thiophene, are useful in the treatment of inflammation and/or pain.